After all, how dangerous is it when comparing 'new coronavirus infection and influenza'?

On December 15, 2020, one year after the discovery of the

new coronavirus infection (COVID-19) , COVID-19 and seasonal flu were compared with fully qualified and uniform data. The results of the study were published in the British Medical Journal. This treatise once again highlights the differences in mortality risk and symptoms between COVID-19 and influenza.

Comparative evaluation of clinical manifestations and risk of death in patients admitted to hospital with covid-19 and seasonal influenza: cohort study | The BMJ

Study: COVID-19 patients have greater risk of health problems, mortality than those with flu

World Health Organization (WHO) Secretary-General Tedros Adhanom said, 'Coronavirus disease (COVID-19) is not as infectious as influenza,' and President Trump said, ' COVID-19 is more lethal than influenza. COVID-19 and influenza have often been compared, such as posting on Facebook saying ' low. '

The new coronavirus is not as infectious as influenza, 'said the WHO Executive Director, urging countries to detect infected people early-GIGAZINE.

by UN Geneva

Regarding this comparison between COVID-19 and influenza, a research team led by Ziyad Al-Aly, director of the Center for Clinical Epidemiology at Washington University in St. Louis, said, 'Government agencies, public health authorities, and even the general public have various forms. I have compared COVID-19 with influenza, but they are based on data and statistics obtained in different ways, and no comparison has been made under the same conditions so far. ' I'm pointing out.

Therefore, the research team conducted research using the electronic medical database of the United States Department of Veterans Affairs (VA) , the largest integrated medical care delivery system in the United States . VA provides medical benefits as part of its welfare program for veterans, and its database keeps a record of the medical services provided by a total of 1255 medical institutions to a total of more than 9 million veterans. It is said that it is.

As a result of extracting cases from this VA database, a record of 54,281 patients diagnosed as positive by influenza test between January 1, 2017 and December 31, 2019, and February 1, 2020 Records of 9125 patients who tested positive for COVID-19 on June 17 were found. As a result of further narrowing down the data to match the conditions such as the length of hospital stay before and after the diagnosis, the final data of 12,676 influenza patients and 3641 COVID-19 patients remained. The average age of influenza patients was 70.25 years, the average age of COVID-19 patients was 69.03 years, and the overall average age was 69.98 years.

And as a result of the research team collating both records, it was found that 'COVID-19 is nearly five times more likely to die than influenza.' Specifically, of the 12,676 influenza patients, 674 (5.3%) died, while of the 3641 COVID-19 patients, 676 (18.5%) died.

The following is a graph comparing the number of deaths per 100 patients (vertical axis) of influenza patients (blue) and COVID-19 patients (yellow) by the number of days (horizontal axis) after admission. It can be seen that the mortality rate of influenza patients has almost leveled off around the 20th day of hospitalization, while the mortality rate of COVID-19 patients has consistently increased sharply from the first day of hospitalization to 60 days. ..

In addition, the following is a graph showing the number of patients who also used a ventilator (top) and the number of patients who received intensive care (bottom). As a result of comparing the use of medical resources by COVID-19 patients and influenza patients, 'COVID-19 patients are four times more likely to need a ventilator than influenza patients and need treatment in the intensive care unit. The probability is also 2.5 times higher. ' The average length of hospital stay for COVID-19 patients was 3 days longer than that for influenza patients.

The study also found that COVID-19 patients were about 9 more likely to develop diabetes during hospitalization than influenza patients by about 9 per 100 patients. Regarding this, Al-Aly said, 'People who were not diabetic before getting COVID-19 also suddenly had a sudden rise in blood sugar and needed a large amount of insulin . Is this diabetes transient or long-term? I don't know if it's something like that because it's only been a year. '

In addition, a study published in June 2020 also shows that 'COVID-19 may cause diabetes even in healthy people.' The study suggests that infection with the virus destroys insulin-secreting cells, causing diabetes.

'Infection with the new coronavirus can cause diabetes even in healthy people,' researchers point out-GIGAZINE

Not only diabetes, but also various complications such as renal disorder, liver disorder, hemorrhagic shock , hypotension suspected to be visceral disorder, pulmonary embolism , deep vein thrombosis , stroke , acute myocarditis , arrhythmia and sudden cardiac death. However, the results showed that COVID-19 patients were at higher risk than influenza patients.

Based on these research results, Al-Aly said, 'We sometimes call COVID-19 a viral infection of the respiratory system, but if you look at the clinical results, you can see the brain, liver, heart, kidneys, blood vessels, etc. There is a risk of damage to a wide area. This is a devastating result. '

in Science, Posted by log1l_ks