A low-carbohydrate diet can lead to diabetes

Many people go on a diet to pursue a healthy or ideal body, and various methods such as low-sugar diets and low-fat diets are popular. The ketogenic diet, which drastically reduces carbohydrate intake and supplements with lipids, has been devised, but experts say that if carbohydrates are drastically reduced, it may cause diseases such as diabetes. Advise.

Low carbohydrate intake correlates with trends of insulin resistance and metabolic acidosis in healthy lean individuals - PubMed


Low Carb Intake Linked to Insulin Resistance | Lifespan.io


Historically, low-carbohydrate diets have been used for weight loss in obese people and those with type 2 diabetes. A low-carbohydrate diet, especially a ketogenic diet, has been found to be very effective in inducing rapid weight loss in both obese and overweight individuals, but the effect on normal weight individuals is It has not been fully clarified yet.

Therefore, Fatima Reshed of the Dasman Diabetes Institute and others recruited 120 healthy people with normal BMI and conducted a survey to record their physical activity and diet for a week. Participants were divided into three groups based on how much carbohydrate they ate, and blood samples were collected from all of them.

As a result, although some numerical values such as neutral fat, total cholesterol level, and good cholesterol level were almost similar in the three groups, there was a significant difference in the function to keep glucose in the body constant (glucose homeostasis). It turns out there is.

According to Reched et al., among the three groups, those who ate less than 45% of their total calorie intake during the week and fell into the 'low-carbohydrate intake group,' were more likely to consume C-peptide, a precursor of insulin. It was found that there was a positive correlation between the increase in , and the secretion of interleukin-6 (IL-6) and interleukin-17A (IL-17A), which promote inflammation. In particular, IL-6 is known to cause

insulin resistance and type 2 diabetes, and it was suggested that following a low-sugar diet facilitates the secretion of these substances.

'This study is the first to show that dysfunction of glucose homeostasis and elevation of plasma C-peptide can induce inflammation in normal-weight healthy individuals following a low-carbohydrate diet. 'Low-carbohydrate diets can be detrimental to healthy people.'

in Science,   Junk Food, Posted by log1p_kr