It turns out that people whose viral load has decreased with anti-HIV drugs have almost zero possibility of spreading AIDS through sexual activity



A data survey of thousands of people in 25 countries revealed that once the viral load was reduced, people taking anti-HIV drugs had almost zero risk of spreading the virus through sex thereafter.

The risk of sexual transmission of HIV in individuals with low-level HIV viraemia: a systematic review - The Lancet

https://doi.org/10.1016/S0140-6736(23)00877-2



People on HIV meds have 'almost zero' chance of spreading virus via sex once levels are low | Live Science

https://www.livescience.com/health/hiv/people-on-hiv-meds-have-almost-zero-chance-of-spreading-virus-via-sex-once-levels-are-low



The risk of HIV transmission from patients with low-level HIV viremia receiving 'antiretroviral therapy (ART)' with multiple antiviral agents has important public health implications in resource-limited settings using alternatives to plasma-based viral load testing. So Dr. Laura N. Broyles, an infectious disease doctor at Grady Memorial Hospital in Atlanta, Georgia, and her colleagues gathered information about sexually transmitted infections in people with varying levels of HIV.

Dr. Broyles and colleagues published from January 2010 to November 2022, various levels of viremia and sexual transmission of couples infected with HIV only on one side (serum mismatched couples) Cross-search. We found 244 studies, of which 8 studies of 7762 seromismatched couples from 25 countries were analyzed.

As a result, three studies showed that an HIV-infected partner with a viral load below 200 copies per ml did not transmit HIV to the other partner.



In addition, four
None of the 322 infections identified in the prospective study were from patients who were considered to be stably virally suppressed on ART.

Among all studies, there were 2 cases in which the most recent viral load was less than 1000 copies per ml among patients diagnosed with HIV infection in the past.

Based on these findings, Dr. Broyles et al. expressed the view that if the amount of HIV virus is less than 1000 copies per ml, the risk of infecting someone is almost zero.

``This finding is important because the risk of sexually transmitted HIV infection is almost zero when the viral load is low,'' said Dr. Lara Vozinov, co-author of the paper and World Health Organization.

The results of Dr. Broyles et al. were published in the academic journal The Lancet, and will be presented virtually at the 12th International AIDS Society HIV Science Conference.

in Science, Posted by logc_nt