The latest research suggests that childhood trauma may even affect Alzheimer's in old age

Alzheimer's disease is a symptomatology of cognitive decline in the brain, which is mainly caused by aging. In addition, various factors are thought to influence the development of Alzheimer's disease, such as doubling the risk due to drinking and reporting that the risk increases when sleeping time is short, but it was announced in 2021. The latest study suggests that 'childhood trauma' may affect cognitive decline after aging.

Adverse childhood circumstances and cognitive function in middle-aged and older Chinese adults: Lower level or faster decline?

Association between different dimensions of childhood traumatization and plasma micro-RNA levels in a clinical psychiatric sample --PubMed

A possible link between childhood trauma and Alzheimer disease? --Padirac Innovations' blog

In a paper published in March 2021 by Shi Chen, who studies health care as well as Juor Lin , who studies health economics at Yale University in the United States, a long-term relationship between childhood conditions and cognitive aging The relationship was investigated. It shows that status, including family socio-economic status, neighborhood connections, friendships and health status are closely related to both the level of cognitive impairment and the rate of cognitive decline.

In contrast, childhood neighborhood safety and community security only affect the level of cognitive impairment, and childhood relationships with mothers only affect the rate of cognitive decline. .. Taken together, the effects of poor environment in childhood are more pronounced at the level of cognitive impairment than at the rate of cognitive decline, according to a study by Lin and Chen.

Researchers also argue that such a decline in cognitive function eases the relationship with the mother. On the other hand, the same effect is not seen in the relationship with the father, and it seems that this difference can be explained by the various roles played by the father and mother at home.

A similar study by the German Center for Neurological Disorders focused on the miRNA component of human genes and investigated the relationship between Alzheimer's disease and childhood trauma. The study recorded that multiple miRNA samples, which may have been meaningfully associated with childhood trauma scores, were also significantly associated with Alzheimer's disease.

There have been quite a few studies done from the perspective that 'childhood experiences have long-term health effects', but none of them are elusive and unclear. That's right. Under such circumstances, discoveries focusing on miRNAs that affect the development and function of the nervous system are expected to have more meaningful effects than ever before.

in Science, Posted by log1e_dh