A person who received the new coronavirus vaccine collects blood every day to investigate 'How did the virus antibody titer change?' And released it as data.



@Souyakuchan, who said that he actually inoculated the new coronavirus vaccine, asked 'how the virus antibody titer changed' from the first vaccination to the second inoculation, repeating blood sampling every day. It was clarified by examining the value.

Murakumo Kusuri (Drug Discovery) ???? ㋻ Sai (@souyakuchan) / Twitter
https://twitter.com/souyakuchan

@Souyakuchan, who inoculated the new corona virus vaccine 'BNT162b2 ' developed by Pfizer, a major American pharmaceutical company, and BioNTech, a biotechnology company, on March 19, 2021, said, 'Because it's a big deal, I collect blood every day and antibody titer. I'm going to see the changes in the antibody titer, 'so I'm tracking how the antibody titer changes from the first inoculation while actually collecting blood.



As for the impression on the day of vaccination, he tweeted, 'There is slight tenderness in the deltoid muscle at the time of vaccination and pain when raising the upper arm. If you feel comfortable, you will not feel any discomfort.' The next day, 'If you raise the upper arm slightly in the abduction direction on the struck side, the inoculation site (deltoid muscle) hurts (raising in the shoulder flexion direction does not hurt so much). There is tender pain. Redness and swelling. , No feeling of heat. No other special symptoms. ”At the same time, I posted a photo of the blood sampling taken to measure the antibody titer.



Three days after the vaccination, the pain at the inoculation site almost disappeared, and the notable symptoms disappeared. Twelve days have passed since the vaccination with almost no change in physical condition, and the measurement results of the antibody titer by CLIA at this point (up to 11 days after the vaccination) are published as a graph. The value of IgG jumped sharply 10 days after vaccination, but IgM remained almost flat.



At 14 days after vaccination, IgM finally increased and became positive.



After that, @souyakuchan will be vaccinated with the second vaccination 21 days after the first vaccination. Five hours after the second vaccination, he had no symptoms such as pain, malaise, or fever. The graph below shows the changes in antibody titers from the first vaccination to 19 days later. Since the peak antibody titer from the first vaccination came on the 16th and 17th days, it seems that 'the second vaccination is given 3 weeks after the first vaccination' is timely. @souyakuchan's and it says .



He also tweeted that the pain at the inoculation site was the same as the first one, and one day after the second vaccination, the fever began to rise and he felt a slight pain in the muscles of the whole body like when he was infected with influenza.

And the body temperature rises up to 38.4 degrees in 2 days from the second vaccination. However, it is reported that the body temperature dropped to 37.4 degrees in the morning two days after the second inoculation, and dropped to almost normal temperature during the day.



Therefore, the graph below summarizes the changes in antibody titer (IgG) from the first vaccination with the new coronavirus to 30 days later. With changes in the actual values, 'Don't relax because you haven't been immunized for a while after the first vaccination.' It is a graph that makes it easy to understand visually.



Please note that the number of subjects is '1' because the graph was created from the blood sampling data of @souyakuchan. However, similar changes in antibody titers have been reported by people who have been vaccinated in the same way, so the trend of the graph is 'you can think of it as known evidence,' @souyakuchan tweeted.



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