Possibility of medical instruments that can detect hypoglycemia from the human breath like a diabetes detection dog

Sometimes blood glucose levels in diabetic patients are significantly lower, and delay in treatment may be associated with the danger of life. By discovering that the Institute of Metabolic Science (IMS) of Cambridge University contains chemicals in respiration of patients suffering from hypoglycemic attacks, "Diabetes detection dogThere is a possibility that medical instruments that detect hypoglycemic condition from exhalation appear as shown in Fig.

Exhaled Breath Isoprene Rises During Hypoglycemia in Type 1 Diabetes | Diabetes Care
http://care.diabetesjournals.org/content/39/7/e97


Diabetes sniffer dogs? 'Scent' of hypos could aid development of new tests | University of Cambridge
https://www.cam.ac.uk/research/news/diabetes-sniffer-dogs-scent-of-hypos-could-aid-development-of-new-tests

Lowering the blood sugar level of diabetic patients may cause symptoms such as hands and feet, body tremor, disorientation, fatigue. If you do not take measures to raise your blood sugar as soon as possible, your level of consciousness may decline, or in severe cases you may get into a disturbance of consciousness or coma. Depending on the person, seizures may begin immediately from mild symptoms, so careful attention should be paid to changes in blood glucose levels.

A IMC researcher who reads the diabetes detection dog's report that can sepa- rate the change in blood glucose level thought that "When the blood sugar level changes, a certain chemical substance increases in the expiration." In order to verify this hypothesis, the research team wasType 1 diabetesUnder the cooperation of eight female patients, we examined the condition during hypoglycemia by mass spectrometry. As a result, when it falls into hypoglycemia,IsopreneTurned out to rise significantly. Some said that some people recorded a double rise.

Dr. Mark Evans, a doctor at the University of Cambridge, says, "Isoprene is one of the most common natural chemicals in human breathing, but I do not know how detailed it is from the body," I am talking. Dr. Evans and others think that it is a by-product of cholesterol production, but I do not know why the amount of isoprene will drop when the blood glucose level drops significantly.


Humans can not detect the presence of isoprene by olfaction, but I also know that it can be easily split off for olfactory superior dogs. In the future, the research team can use the measuring instrument which can easily measure the blood glucose with a method such as diabetes detection dog and alcohol test even without using the conventional blood glucose measuring machine stabbing the needle in the finger, and the same level as the diabetes detection dog We are going to develop new medical devices for diabetes such as detectors that can detect isoprene.