Three dimensional protein molecular model that can be assembled / decomposed produced with 3D printers

To make 3D models with 3D printers that allow you to see and touch the interior and surface structure of proteins using 3D printers,Masaru KawakamiAssociate professor succeeded. Until now it was simpleSpherical rod model, Crystal Laser Engraving, CG and other proteins that I was looking at can actually be understood to the hand while feeling the characteristics of the surface.

Japan Advanced Institute of Science and Technology | News | [Press Release] Development of new molecular model manufacturing method applying 3D printing technology - Teaching materials and research tools that can intuitively understand complex protein structure and function application-

In addition, the technology to make this model has been patented, and in addition to 3D printing "Disappearing mold"By covering the surface with a transparent and resilient material like gummy candy using the technique called" Surface structure "can be reproduced while enhancing strength. Since I was able to borrow the real thing this time, I decided to take a picture of the figure while touching Petapeta.

I entered cardboard and a set of models arrived.


The model "DNA binding protein (TATAbinding protein) and an activator binding to it" is as follows.


The irregularities of the surface made of silicon are actually the same as protein, and it is possible to understand the features while touching with hand.


When put on the hand of an adult male it is like this.


Since the model is coupled with a magnet, it can be taken as a polo.


It is like this when actually removing it.


It can be further broken down.


The transparent parts are as follows.


The appearance of actually disassembling can be seen in the following movie.

I tried touching a silicon-made protein molecule model made by 3D printer - YouTube


This model is waterproof so it can be put on water OK.


Normally it's hard to see a little inside ... ....


When it is put in water, the surface becomes clear and transparent and contents can be seen as being clear.



The model of "hemoglobin tetramer" is as follows.


Looking up it is like this.


This model can also be disassembled.


It is divided into four.


A model of "drug adenosine receptor (GPCR)" which is a drug target of Parkinson 's disease is like this.


There are parts like this.


After disassembly is as follows.


Currently it is possible to produce protein solid models with molecular weight up to about 50,000, so it seems that it is supposed to be used by universities and pharmaceutical companies.