Nov 15, 2022 16:55:00

Pfizer and Moderna are conducting research on the risk of myocarditis and pericarditis after vaccination with the new corona vaccine

Regarding vaccination against the new coronavirus infection (COVID-19), cases of

myocarditis and pericarditis , which are thought to be caused by the vaccine, although very few, have been reported . The news media NBC News reported that pharmaceutical companies such as Pfizer and Moderna, which developed vaccines, are studying the long-term effects of these symptoms, which are especially common in young people.

Myocarditis after Covid vaccine: Research on long-term effects underway
https://www.nbcnews.com/health/health-news/myocarditis-covid-vaccine-research-long-term-effects-rcna55666

Davion Miller, a 22-year-old living in Detroit, Michigan, USA, experienced symptoms such as chest pain, fatigue, and shortness of breath two days after receiving Pfizer's COVID-19 vaccine for the first time. And one week after the vaccination, he was found unconscious in his bathroom and taken to the hospital. Mr. Miller, who recovered with treatment, was diagnosed by a doctor as having myocarditis or pericarditis and was instructed not to receive a second Pfizer or Moderna vaccination.

Miller is one of the very rare patients who has experienced myocarditis after receiving the Pfizer or Moderna COVID-19 vaccine. According to the Centers for Disease Control and Prevention (CDC) , more than 100 million vaccinations have been administered in the United States since the second half of 2020, and about 1,000 cases of vaccine-related myocarditis or pericarditis, mainly in young men. It has been reported.

Most people who develop myocarditis or pericarditis after vaccination make a full recovery, but studies so far have followed patients only for months, and some doctors believe that these symptoms are more likely to affect the heart. I am concerned about the long term impact. Pharmaceutical companies are conducting studies to examine the long-term risk of heart disease after vaccination with COVID-19.

According to NBC News, Moderna has already launched two trials, and Pfizer plans to launch a trial involving up to 500 young adults in the coming months. According to the U.S. Food and Drug Administration's (PDF file)

approval letter (PDF file) for the study, some studies followed people who developed myocarditis or pericarditis for five years and asked if they had symptoms. It is said that a comparison will be made if it is not. The first findings are expected to be published in 2023.

The FDA declined to comment to NBC News, saying Moderna and Pfizer trials are ongoing. But FDA officials argue that the chances of developing heart disease after receiving the COVID-19 vaccine are very low, and that data from Florida state these illnesses do not lead to death. “There is no evidence of an increased risk of death following mRNA vaccination compared to unvaccinated individuals. , suggesting that unvaccinated people are at higher risk of death,' the official said.

According to the CDC, most people who develop myocarditis or pericarditis after receiving the COVID-19 vaccine are young men aged 16 to 24, with 52.4 cases per million doses for Pfizer and per million doses for Moderna. It is estimated that there are 56.3 onset cases. On the other hand, Johnson & Johnson's vaccine has not seen similar symptoms post-vaccination, and Novavax claims no similar concerns have been raised post-vaccination.

The main symptoms of myocarditis are chest pain, shortness of breath, and palpitations, and it is known that the

risk of myocarditis increases even after the third booster vaccination, but the risk of myocarditis with the booster vaccination is the second. reportedly lower than inoculation.

Dr. Nicola Klein, a vaccine expert at Kaiser Permanente , an American health care organization, said post-vaccination myocarditis was generally milder than that caused by COVID-19, with most patients completely He explains that he can recover. In a paper published by the CDC in October 2022, symptoms of post-vaccination myocarditis improved significantly after 90 days, but still had problems with physical activity and abnormalities in cardiac MRI images. It has been reported that some patients

Dr. Paul Burton, Moderna's chief medical officer, said that while scientists still don't know the exact mechanism by which the COVID-19 vaccine causes heart disease, the heart's immune response to the spike protein produced by the body after vaccination is the heart's disease. I expect that it can cause inflammation. Moderna is planning additional trials not only in the United States, but also in the European Medicines Agency and five European countries. ``The benefits of being vaccinated outweigh the risks of being vaccinated, which is absolutely true for myocarditis,'' Burton said, recommending a booster shot.