Nov 08, 2022 23:00:00

How will the incidence of myocarditis and pericarditis change in COVID-19 unvaccinated individuals?

Cases of

myocarditis and pericarditis have been reported in people who have been vaccinated against the new coronavirus infection (COVID-19). In response, a paper examining the incidence of myocarditis and pericarditis in people who have not been vaccinated against COVID-19 has been published, and how the presence or absence of COVID-19 infection affects myocarditis and pericarditis. It became clear that

JCM | Free Full-Text | The Incidence of Myocarditis and Pericarditis in Post COVID-19 Unvaccinated Patients—A Large Population-Based Study
https://www.mdpi.com/2077-0383/11/8/2219

The Incidence of Myocarditis and Pericarditis in Post COVID-19 Unvaccinated Patients-A Large Population-Based Study - PubMed
https://pubmed.ncbi.nlm.nih.gov/35456309/

Previous studies have reported an increased risk of myocarditis and pericarditis after vaccination with the COVID-19 vaccine, and this has been shown to be the same even with booster vaccination.

Myocarditis risk from COVID-19 vaccine increases even with booster vaccination - GIGAZINE

Because studies exist on the incidence of myocarditis and pericarditis in COVID-19 vaccinees, a research team led by Ortal Tuvali at the Kaplan Medical Center in Israel and the Hebrew University of Jerusalem said: 19 incidences of myocarditis and pericarditis in unvaccinated individuals”.

Myocarditis and pericarditis are known potential acute sequelae of COVID-19 infection, which are known to result from adaptive immune responses . To determine the incidence of myocarditis and pericarditis in unvaccinated COVID-19 patients, the research team collected data from Israeli health services organization Clarit Health Services from March 2020 to January 2021. We are conducting a retrospective cohort study , collecting adult data from 196,992 unvaccinated individuals infected with COVID-19 during the period. In the study, patients were examined 10 days after a positive PCR test to determine if they had developed myocarditis or pericarditis. Follow-up for each patient was censored on 28 February 2021, but each patient received a minimum of 18 days of follow-up.

In the study, we also analyzed the data of 590,976 ``unvaccinated adults who have never been diagnosed as positive in the PCR test for COVID-19'' as a comparison target for the above-mentioned subjects.

Analysis revealed that 9 of the unvaccinated COVID-19 patients developed myocarditis (0.0046% incidence) and 11 developed pericarditis (0.0056% incidence). It is On the other hand, among the unvaccinated people who were not infected with COVID-19, 27 developed myocarditis (incidence rate 0.0046%), and 52 developed pericarditis (incidence rate 0.0088%). It was also found that

It was also found that whether unvaccinated people developed COVID-19 was not associated with the incidence of myocarditis and pericarditis. On the other hand, age and male sex were significantly associated with the incidence of myocarditis, and peripheral vascular disease and male sex were also found to be significantly associated with the incidence of pericarditis.

It has also been confirmed that the ``incidence of myocarditis and pericarditis'' does not increase after unvaccinated people recover from COVID-19.