The influence of the new corona shows the possibility that 'male fertility will decline'
Coronavirus infection (COVID-19) not only causes respiratory symptoms, but also affects major organs such as blood , heart, lungs, and kidneys, and cases of damage to brain tissue have also been reported. I have. New studies have shown that men with COVID-19 may have reduced fertility.
Evaluating the impact of COVID-19 on male reproduction in: Reproduction Volume 161 Issue 2 (2021)
COVID-19 and male reproductive function: a prospective, longitudinal cohort study in: Reproduction --Ahead of print
Men May Be Less Fertile in The Aftermath of COVID-19 Infection, Scientists Warn
It is known that the new coronavirus (SARS-CoV-2) uses an enzyme called angiotensin converting enzyme 2 (ACE2) when it invades the human cell. ACE2 is abundant in a wide range of the human body, especially in the lungs, gastrointestinal tract, and heart, and in men, ACE2 is also present in a high proportion in the testis. Therefore, it is hypothesized that 'COVID-19 is more likely to become severe in men by hiding SARS-CoV-2 in the testicles'.
Hypothesis that male new coronavirus infection is likely to become serious due to 'testicles' --GIGAZINE
A research team at Huazhong University of Technology in Wuhan, China, investigated the potential impact of SARS-CoV-2 on male fertility by analyzing existing studies. As a result, although it cannot be argued that the effects of COVID-19 have reduced fertility, 'we propose an urgent need to track male patients recovering from COVID-19,' SARS said. -The research team argues that close attention should be paid to the potential of CoV-2 to cause reduced fertility.
Researchers at the University of Giessen at the University of Giessen in Germany and the University of Allameh Tabatabay in Iran also collected semen from 84 patients who were diagnosed with COVID-19 and headed for recovery from 105 healthy controls. We conducted a study to compare with the collected semen.
Both semen were collected at 10-day intervals for approximately 60 days, and analysis was performed on ACE2 activity in semen, markers of sperm inflammation and oxidative stress, and sperm quality. As a result, there was a clear difference between the two, and the man diagnosed with COVID-19 had problems with various aspects of semen.
For example, men with COVID-19 were found to have more than double the markers of sperm inflammation and oxidative stress compared to men of the same age in the control group. It was also found that COVID-19-positive men were significantly inferior to healthy men in terms of semen volume, sperm motility, sperm count, and sperm concentration.
'These effects on sperm cells are associated with reduced sperm quality and fertility,' said Behzad Hajizadeh Maleki, a sports scientist at the University of Giessen at the University of Giessen. The effects on sperm quality tended to improve over time, but the effects on fertility in COVID-19 patients were still persistent, and the degree of adverse effects was associated with the severity of COVID-19. Stated.
The results of this study followed men who recovered from COVID-19 for 60 days, but it is unclear what effect they will have on men over that period. The researchers argued that more extensive research and follow-up was needed to validate the conclusions drawn from this study and accurately assess the effect of COVID-19 on male fertility.
in Science, Posted by log1h_ik