Drinking alcohol until fainting doubles the risk of dementia

Alcohol is a luxury item that is widely loved around the world, but research has shown that drinking alcohol

damages immune function and increases the risk of stroke, and alcohol has various adverse health effects. Is supposed to give. A newly published study suggests that consuming large amounts of alcohol overnight may 'double the risk of dementia' and 'decrease empathy.'

Association of Alcohol-Induced Loss of Consciousness and Overall Alcohol Consumption With Risk for Dementia | Dementia and Cognitive Impairment | JAMA Network Open | JAMA Network

Drinking Until You Pass Out Is Linked to Doubled Risk of Dementia, Huge Study Reveals

Differential brain responses for perception of pain during empathic response in binge drinkers compared to non-binge drinkers --ScienceDirect

Brain scans reveal a critical link between binge drinking and empathy

For example, even if you drink 1 liter of alcohol, the situation is completely different between 'drinking 1 liter a day' and 'drinking 1 liter a month'. However, the research so far has mainly focused on the 'average consumption of alcohol', and the focus on the 'drinking pattern' of how much alcohol is consumed in what span. Was almost nonexistent. So a research team led by Mika Kivimaki of University College London examined the association between subjects' drinking patterns and dementia risk from the results of seven large-scale studies conducted to date.

The total number of subjects in the seven large-scale surveys covered in this study was more than 130,000. Of these, more than 96,000 said they had drank until they fainted, and 10,000 said they had drank until they fainted within the last 12 months.

When the research team analyzed the results of the follow-up survey, the subjects who answered that they had drank until they fainted within the last 12 months were those who had the same amount of alcohol but did not drink until they fainted. It turns out that the risk of dementia is doubled compared to. The risk is doubled for all kinds of dementia, including Alzheimer's disease, regardless of age or gender. On the other hand, the risk of dementia for heavy drinkers (more than 2.8 liters of beer per week) was only 1.2 times higher than that of moderate drinkers (less than 2.8 liters of beer per week).

The study suggests that not only average alcohol consumption, but also drinking patterns have a significant impact on health. The research team explained that the act of drinking until fainting has a great effect on cognitive function: 'Ethanol directly stimulates

NMDA-type glutamate receptors in neurons to produce large amounts of glutamate, and this glutamate kills brain cells. It causes the effect of causing it. '

As mentioned above, in addition to the research that 'drinking a large amount overnight' increases the risk of dementia, a new research that 'reduces empathy' has been newly announced. A study conducted by a research team at the University of Sussex found that subjects who had 'drinking more than 1.4 liters of beer (140 ml in terms of pure alcohol) overnight' within the last 30 days were injured in their limbs. While showing the picture of, 'Imagine the pain of a person with this limb'. During the response, subjects were scanned for brain activity by fMRI , and 'empathy' was measured from the status of brain activity.

The results of the experiment confirmed that subjects who swallowed within the last 30 days compared to the control group needed to work harder to imagine the pain of others. Professor Theodora Duka, the lead author of the paper, said, 'This result suggests that heavy drinkers may have difficulty detecting the pain of others. In the case of diversion of brain resources elsewhere. Heavy drinkers may have a hard time empathizing with others. '

in Science, Posted by darkhorse_log