If you have a high-fat diet when stressed, it is easier to get fat than usual


by

Daniel Bachhuber

The same amount of high-fat diet, when stressed, showed that weight gain is greater than when not feeling stressed in experiments with mice. Researchers believe that this can happen to humans as both mice and humans have the same system.

Amygdala NPY Circuits Promote the Development of Accelerated Obesity under Chronic Stress Conditions-ScienceDirect
https://www.sciencedirect.com/science/article/pii/S1550413119301858

Eating While Stressed Could Mean Extra Weight Gain, Mouse Study Finds
https://www.livescience.com/65326-stress-eating-weight-gain.html

In this study, the mice were divided into 'a group that chronically stressed by pulling away from friends and pouring a thin bed into the bed' and a group placed in a non-stressed environment ', either normal or high fat in each group. We observed and analyzed what kind of reaction it gives by eating.

As a result of the experiment for two weeks, the mice that took a normal diet in a stressed environment had almost the same weight as the mice that lived on a regular diet in a non-stressed environment, while high fat in the stressed environment It was shown that the mice who ate their diet gained more weight than the mice who ate high-fat diets in a stress-free environment.

The team of Professor Herbert Herzog, head of the Galvanic Research Institute of the Galvan Institute in Australia, who conducted the study, then opened the mouse head and tried to determine what was happening in the brain.

The researchers say that this phenomenon is related to the neuropeptide Y (NPY) produced from the hypothalamus and amygdala in response to stress. The hypothalamus is located in the center of the mouse or human brain and controls appetite and hunger, and the amygdala responds to feelings such as anxiety and stress. In the hypothalamus, NPY is known to stimulate food intake.


by

Media News

Researchers who thought that NPY was related between weight gain and stress treated mice to stop NPY generation. When the hypothalamus blocks NPY, even under a high-fat diet, stressed mice gain weight only as much as non-stressed mice. This experiment has shown that NPY is involved in weight gain for stress eating.

Previous studies have also shown that NPY also interacts with the hormone ' insulin ', which is related to the amount eaten by humans and mice. When a person eats, they absorb glucose from the blood and raise insulin levels to signal the 'stop eating' to the hypothalamus. The mice that were chronically stressed and fed a normal diet in this experiment had slightly higher levels of insulin than non-stressed mice. On the other hand, mice in a stressed environment fed a high fat diet seem to have 10 times as high insulin levels as mice fed a normal diet in a non-stressed environment.

As insulin levels rise around the amygdala, brain cells become less sensitive to hormones. Then, more NPY will be generated, and the appetite will be enhanced even though the body's ability to burn energy declines. It is unclear why the brain has such a mechanism, but Herzog who did the research said, 'The absence of food is a great stress, and eating so much against such stress is a survival technique. 'I think that'.


by rawpixel.com

This study was conducted for mice, but since mice and humans have the same NPY system, the same thing as described above is considered to be 'highly likely to occur in humans'. In addition, this research is considered to be useful for obesity control, and researchers want to do further research.

in Science,   Junk Food, Posted by darkhorse_log