Obviously that evening-type humans who tend to stay up late are more unhappy and mental health is also unfavorable

by Alexandra Gorn

I often hear indications that staying up late is an enemy of health and that early rising is important for sending an excellent day, but as I often hear, "I can not get up early and I have a night type life" There are many people who think that. However, according to the latest research published at Nature Communications of the scientific journal on January 29, 2019, the person staying up late is overall more unhappy than the early rising person, and the possibility that mental health may be bad It seems to be high.

Genome-wide association analyses of chronotype in 697,828 individuals providing insights into circadian rhythms | Nature Communications
https://www.nature.com/articles/s41467-018-08259-7

Being a Night Owl Really Can Hurt Your Mental Health
https://www.livescience.com/64628-night-owl-mental-health.html

The human sleep patterns are people, but rough classification is "morning human" who can get up early and can act vigorously, "morning human" who is not weak in the morning, "head of the evening" whose head becomes clear at night, and 2 It can be classified into three, "intermediate human being" which is intermediate between the two. These are also called circadian rhythms (body clock), but it is clear from the latest research that this circadian rhythm is deeply involved with human genetic information.

Research was conducted to analyze the circadian rhythm and human genetic information in detail, and in previous studies, 24 regions of the human genome were thought to be related to "early rising", but in fact 351 It is clear that the area is related to "early rising". In addition, it has been found that those with genetic variants most related to early rising among the research samples tend to fall asleep more than 30 minutes on average on average for those with fewer variants I will.

In addition, this study finds that certain regions of the human genome are related to "retinal" in addition to "circadian rhythm". This finding seems to support the previously proposed theory that "the ability of the brain to detect light through the retina sets the body clock to sleep and wake up in a 24-hour cycle".

by Gregory Pappas

Samuel Jones, who is studying sleep patterns and genetics at the medical department of Exeter University in the UK, is the first author of the paper. "There is a morning person and a night person, because the function of human beings' ability to normalize the body clock by responding to external light signals" of human beings is Because it is different from morning type and night type) ".

The study of Mr. Jones et al. Analyzed genome-wide association of 697 7828 genetic information stored by 23 and Me of non-profit health project and DNA analysis service called Biobank . In addition, Mr. Jones and others used the same research sample and succeeded in "identifying the locus related to circadian rhythm" in April 2018.

Researchers identify genetic loci associated with morning and night type with about 700,000 genes - GIGAZINE

Among the subjects who provided genetic information for research, people asking for participation from 23 and Me, are asked by "questionnaire survey" whether "myself type is morning, night type or middle". However, because there is a possibility of subjects' subjective answers, in the research, we distributed a wristband type activity meter to more than 85,000 subjects who participated in the experiment via Biobank, and the subject's sleep information Collected. In other words, the researcher checked the sleep information of the subject and correctly judged the circadian rhythm of each subject.

As a result of the analysis, it is clear that there is no big difference in the quality of sleep even if there is a difference in sleep timing. Also, contrary to several previous research findings, we were unable to find out that evening-type humans are at increased risk of obesity and diabetes. Instead of newly revealing that there is a clear causal relationship between being susceptible to psychosis such as depression, anxiety and schizophrenia and being a night type person.

In other words, it seems that it became clear that evening-type humans have a higher risk of developing psychosis such as schizophrenia than morning persons, and the happiness degree felt by each person is lower. In addition, as mentioned above, "The quality of sleep is not different", so the causes of falling mental health of the evening human beings and being unable to feel happiness are "poor sleep quality" and "sleep It is also clear that it does not depend on things like "shortage".

Jacquelini Lane, engaged in genomic medicine at the Massachusetts General Hospital who participated in the study, says that there are many unclear points in the relationship between sleep timing and mental health reduction. For reasons why evening-type humans tend to decline mental health more, genetic variants that many morning persons have, physical stimuli obtained by taking sunlight in the morning by getting up early, in general society "9 It is pointed out that the work cycle from the time to 17 o'clock is dominant, and that the unknown effect may be brought about.

Mr. Lane said, "Our research highlights the need to conduct further research on how circadian rhythms are related to mental health, and until the end of those studies detailed mechanism I can only guess. "

by Hutomo Abrianto