Hundreds of immune system genes are shut down when smoking an electronic cigarette

ByEcig Click

Electronic cigarette is approved as "smoking cessation aid"It is said that the electronic cigarette that vaporizes and sucks liquid flavor has less negative impact on health than traditional cigarette burning tar. Nonetheless, as electronic cigarettes have not appeared on the market, research that investigated long-term effects has not been completed yet, research that newly investigated users of electronic cigarettes was published, and electronic cigarettes aspirated Then it turned out that the activities of hundreds of immune system genes declined.

Abstract: Pulmonary Effects of Exposure to Tobacco Smoke and New Tobacco Products (2016 AAAS Annual Meeting (February 11-15, 2016))
https://aaas.confex.com/aaas/2016/webprogram/Paper16208.html


E-cigs shut down hundreds of immune system genes-regular cigs do not | Ars Technica
http://arstechnica.com/science/2016/02/e-cigs-shut-down-hundreds-of-immune-system-genes-regular-cigs-dont/

University of North Carolina at Chapel HillIrona Jasper and his team collected 12 groups of tobacco smokers, smokers of smokers and nonsmokers, sampled mucous membranes of the nose for 3 weeks, and compared genetic data It was. Using the mucous membranes of the nose will also serve as a clue to investigate the condition of the lung that is difficult to collect samples.

A sample of about 600 genes related to the immune system was investigated from the sample. According to the results of investigating conventional tobacco smokers and nonsmokers, it was found that the activity of 53 genes of tobacco smokers was weaker than that of nonsmokers, and even if only smoking a conventional cigarette, some It has been found that there is an adverse effect on the immune system. In addition, with respect to electronic cigarette smokers, it was found that not only was the adverse effect on the same 53 genetic activities as tobacco smokers, but also the total of 358 immunogene activities weakened compared to nonsmokers Did.

Jaspers' research team received this from healthy participantsNeutrophilYaMacrophageWe picked up immune cells with the ability to attack bacteria such as bacteria and soaked them in liquid flavor of electronic cigarette and saw the reaction. In that experiment, it is estimated that smoking of the electronic cigarette will not prevent the bacterial attack, because the activity of the immune cells in the liquid flavor has declined, which is likely to be susceptible to infectious diseases.

ByLindsay Fox

The influence on immune genes also varies depending on the type of liquid flavor, and liquid medicine such as cinnamon and butter has the strongest adverse effect. The additives included in these liquid flavors are the safety standard certification certificate given to food additives approved by the US Food and Drug Administration (FDA)GRASAlthough it is a substance confirmed with ", the influence at the time of suction has not been tested. Mr. Jasper said, "It is often that we do not know what will happen to the human body by aspirating fragrances like those used for liquid flavors in electronic cigarettes, and we are standing at the entrance to understanding the toxicity of perfumes That's it. "