Research found that it can eliminate obesity by burning fat and sugar without dieting

ByAlan Cleaver

Although there are methods such as exercise and diet restrictions in dieting, this also has perseverance in this too, and it can not be continued easily if it does not work hard enough in spiritual and physical matters. Research that is likely to become a new hope for such a diet was done by Mcstar University of Canada, and it became clear that fat and sugar can be burned without doing a hard diet.

Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis: Nature Medicine: Nature Publishing Group
http://www.nature.com/nm/journal/vaop/ncurrent/full/nm.3766.html

Want to eat like a teen again? Science may have found a way - Latest Hamilton news - CBC Hamilton
http://www.cbc.ca/news/canada/hamilton/news/want-to-eat-like-a-teen-again-science-may-have-found-a-way-1.2862231

Fat contained in mammals includes "Brown fat"When"White fatThere are two fats. The role of the two fats is that brown fat burns fat and sugar to produce heat, white fats store neutral fat. Most of the adipocytes in the human body are white fats existing around the skin or the internal organs, while the brown adipose is around the neck and shoulders of children before puberty, and decreases with each age To goPrevious studyI know from that.

ByTripp

The fact that brown fat can burn fat and sugar, that is, calories to produce heat,Mitochondrial uncoupling protein1 (commonly known as UCP 1) exists. However, when body temperature decreases, brown adipocytes may form in white adipose, which means "Bright fat cellsIt is called. Similar to brown adipose cells, Bright adipose cells can express UCP1the studyI know it, there is work to burn calories.

Previous studies have pointed out "declining activity of brown adipose and bright fat" as a thing common to obese people and type 2 diabetes patients. In other words, obese people and type 2 diabetes patients say "brown fat and bright fat activity are weakening and energy can not be burned".

Also, in another study the body of obese people "Peripheral serotoninIt is confirmed that many hormones exist.SerotoninIn general, the role of "affecting the spirit of human beings and participating in mental and physical stability and mood" is generally recognized, but such types are present in the central nervous system such as the brain, There is only 5% of a certain serotonin. On the other hand, peripheral serotonin is the remaining 95%, it exists in the blood and circulates throughout the body.

ByTanya Dawn

Peripheral serotonin, in simple terms, is "Tryptophan hydroxylase1 (common name: TPH 1) ", and in mice deficient in TPH 1,Serotonin concentration was found to decrease by about 95%doing. In other words, removal of TPH1 means that peripheral serotonin is reduced.

It is the research team of Mcstar University in Canada that connected two points "decline of obesity's brown fat and bright fat" and "the existence of many peripheral serotonin in obese people's body". The research team gave TPH1 by gene manipulation, that is, when mice with little peripheral serotonin were fed with high fat feed, brown adipose and bright fat were activated to burn the calories, so that obesity, fatty liver and diabetes It became clear that obesity complications such as premonitosis do not result, "peripheral serotonin has an action to diminish the activity of brown fat and bright fat".

Professor Gregory Steinberg, one of the research teams, said, "If the amount of peripheral serotonin is excessive, it will be in a state of braking brown fat.If suppressing the expression of peripheral serotonin, the brake applied to brown fat It removes, acts actively and burns fat and sugar, "he told about the research.

ByJeff Drongowski

The research team concluded that "inhibiting TPH1 and decreasing serotonin production may be an effective treatment for co-morbidity of obesity and obesity", and writing the article Currently, TPH1 blockade is under development . If development is realized, brown fat burns calories by taking medicine, so we can expect great help as a diet.