"Half-human brain mouse" became smarter with human brain cells

ByLeo Reynolds

Determining the separation between humans and other animals is a high intelligence brought by highly developed human brains. One research team successfully transplanted such human brain cells into mice and established themselves as "half-human brain" state mice.

The smart mouse with the half-human brain - health - 01 December 2014 - New Scientist

This experiment was conducted by a research team of Dr. Steven A. Goldman of the Medical Center, University of Rochester. Dr. Immaturely taken out from the human fetus who received the organ donationGlial cellsWas transplanted into brain cells of children's mice and observed growth. Then, one year later, human glial cells transplanted into mice proliferated in the form of replacing glial cells originally possessed by mice, and the number of cells which initially had 300,000 cells increased to 12 million cells He said that he did. Dr. Goldman says that "human cells seem to have been driven to the gap by the way cells of human cells expel mouse cells."

The glial cells that proliferated in this experiment are believed to exist in human brain approximately 50 times more than the brain neurons and play a major role in human thinking. Human glial cells are about 10 to 20 times larger than those of mice and are thought to have protrusions that transmit signals over 100 times. In this experiment human glial cells are thought to exist in the central nervous system and play the most advanced role of brain activityAstrocyteThere is a lot of interest in how it affects mouse intelligence by being implanted at the site where it is formed.

ByUBC Public Affairs

An experiment to give sound and electric shock to learn hazard prediction revealed that mice transplanted with glial cells showed higher memory capacity than normal mice and Dr. Goldman said " I can say that it is a smarter mouse than the mouse. "

But at the same time Dr. Goldman says, "This is fundamentally a mouse brain," he emphasizes the view that the brain of the mouse never changed to become a new one. "This does not give the mouse the unique ability of a human being.The transplanted human glial cells have upgraded the mouse brain processing capability but since the mouse brain is still a change, There is not it, "and the movie"Stuart Little"Or"Flower bloom for AlgernonIt does not seem like realizing a genius mouse that appears in "

ByNatasha Fadeeva

The doctor's research team carried out similar transplantation in rats with higher intelligence than in mice, and similarly cell proliferation has been confirmed. Furthermore, similar experiments using monkeys were considered, but they stopped because of "potential ethical issues".

in Science,   Creature, Posted by darkhorse_log