Successfully collecting DNA from the skin of a 75-year old man and making cloned cells



Some countries have banned cloning studies targeting humans, and cloning research has become a subject of discussion. Among them, the American research team used DNA collected from the skin of an adult male I succeeded in cloning human cells.

First Embryonic Stem Cells Cloned From A Man's Skin: Shots - Health News: NPR
http://www.npr.org/blogs/health/2014/04/17/303658757/first-embryonic-stem-cells-cloned-from-a-mans-skin

Scientists Make First Embryo Clones From Adults - WSJ.com
http://online.wsj.com/news/articles/SB10001424052702303626804579507593658361428

A mammalian clone was born for the first time in experiments using sheep 18 years ago from now.dollyThe technology that produced the cloned sheep called clone sheep had a big problem in terms of ethics although it could potentially be used as a cure for myriad diseases if applied to humans. Actually, in ChinaThe world's largest "clone factory" mass-producing cloned pigsIt is made and controversial.


This researchOregon Health and Science UniversityProfessor Robert Lanza andCHA UNIVERSITYThe team led by Professor Young Gie Chung of the University was made for diversion to medical care.

Professors Lanza and his colleagues had already succeeded in making clones from infant and fetal cells already in 2013, but human beings are more likely to become diseases such as diabetes, Alzheimer's disease, Parkinson's disease every year It is a problem that if you can not replicate artificial cells from adult DNA, the value of this technology will halve.

Also, when we collected cells from the very early stage of the fetus, we had the problem of destroying the fetus. Even though I was not born in this world yet, there was a voice saying that this is the same as depriving of life.

So the research team collected DNA from the skin of a 35-year-old man and a 75-year-old male donor. I removed the DNA from the unfertilized egg and inserted the DNA from an adult donor instead. Then the ovum automatically starts reprogramming,BlastocystI will grow up to.


When the blastocyst was cultured in the laboratory, it completely matched the DNA of the donor from the blastocystStem cellsWas born, the stem cells then changed to another type of tissue like cardiac cells. This tissue is thought to be useful for treating many diseases because it can be transplanted to patients without rejection. Shoukhrat Mitalipov, a developmental biologist who was doing research with Professor Lanza, said, "I am very happy that it was proved that our research was right."


This methodHow to make cloned sheepIn another way, "We now have two ways to make clones, but I do not know which method is better," says Lanza.

However, even if the experiment is successful, it does not lead to the conclusion that this can be a complete human clone immediately. Researchers are trying to make clones of monkeys for many years, but there are still no successful cases. I have succeeded in cloning rabbits, sheep, dogs, etc. Even that, I have failed experiments with countless eggs and fetuses for many years.

Some scientists are excited about the advancement of cloning technology from a medical point of view, but on the other hand, there is also a cautious voice as this technology has crossed the boundary line for human cloning . Although the cloned human beings are not born even if the blastocyst made this time is returned to the uterus, it is fully possible that people with knowledge of science may abuse technology.

ByKevin O'Mara

in Science, Posted by logq_fa