"Young reel" comparable to 60-year-old elderly returning to a 20-year-old young succeeded in a mouse experiment


ByKris krüg

A collaborative research team between the US and Australia stopped the aging process of the mouse and succeeded in further rejuvenating the cells. This achievement is "rejuvenation" comparable to converting the aged 60-year old to a 20-year-old young man, but clinical experiments are expected to start in 2014 as well.

Cell - Declining NAD + Induces a Pseudohypoxic State Disrupting Nuclear - Mitochondrial Communication during Aging
http://www.cell.com/retrieve/pii/S0092867413015213

Anti-ageing compound set for human trials after turning clock back for mice | Science | theguardian.com
http://www.theguardian.com/science/2013/dec/20/anti-ageing-human-trials

A joint research team of Harvard University and the University of New South Wales University (UNSW) in Australia succeeded in rejuvenating the cells to a six-month-old mouse state in just one week by medication to a 2-year old mouse.

The research team produces energyMitochondriaFocusing on the organelle called "mitochondria with time"Cell nucleusWe discovered that communication between people is declining and this has been found to be related to the aging process. And, as you age, it decreasesNicotinamide adenine dinucleotide(NAD) was injected into mice cells, the progression of aging was stopped, and furthermore, cell rejuvenation occurred.


Dr. David Sinclair of the research team, Dr. David Sinclair said, "The aging process we discovered is like a married couple, communication is active when young, but communication with living together in a difficult place with time The problem will be solved if communication recovers, "he said. Also co-researcher UNSW Dr. Fellow Nigel Turner said "When I saw the aging process go backward in just one week, I was truly surprised."

Dr. Turner says, "If you listen to the results of this time, you may think that many people are studies to live to the age of 200. However, by understanding and retrograding the aging process, cancer, dementia · type 2 We may be able to delay the progress of the symptoms by activating the cells with diseases such as diabetes that cellular communication declines, "the research results of this time indicate that people are healthy in old age It will lead to living in the future.

ByCandida.Performa

Researchers are convinced that side effects are minimal even when administered to humans because NAD is a substance to be produced in the body, and clinical experiments are scheduled to begin within 2014. However, according to Dr. Turner, it is many years before the "magic tablets" that reverses this aging process become widely used. The majority of the reason is that it requires a huge medicine cost of about 50,000 dollars (about 5.2 million yen) per day when used by people.

in Science, Posted by darkhorse_log