It turns out that the cause of ``brain fog,'' which is a sequela of the new coronavirus that causes a decline in concentration and memory, is bleeding from cerebral blood vessels.



One of the after-effects of the new coronavirus infection (COVID-19) is ``

brain fog ,'' a condition in which your head becomes foggy or hazy, making it difficult to think and concentrate. It was discovered that the cause of this brain fog was bleeding from cerebral blood vessels.

Blood–brain barrier disruption and systemic sustained inflammation in individuals with long COVID-associated cognitive impairment | Nature Neuroscience
https://www.nature.com/articles/s41593-024-01576-9



Leaky Blood Vessels: Underlying Cause of Long COVID “Brain Fog” Discovered
https://scitechdaily.com/leaky-blood-vessels-underlying-cause-of-long-covid-brain-fog-discovered/

Most people infected with COVID-19 will fully recover within a few days, but if symptoms persist for more than 12 weeks after infection, such as fatigue, shortness of breath, poor memory or thinking, or joint or muscle pain. , considered to be long COVID.

Although the incidence of COVID-19 varies internationally, it is estimated that up to 10% of patients who develop COVID-19 will develop long COVID. Just under 50% of patients with Long COVID report neurological effects such as cognitive decline, fatigue, and brain fog.

On February 22, 2024, a team of scientists from Trinity College, University of Dublin, and a research team from FutureNeuro , a research institute that develops technologies for the treatment, diagnosis, and monitoring of chronic and rare diseases, announced that some long-term We reported important findings regarding brain fog and cognitive decline seen in COVID patients in the scientific journal Nature.



This study revealed that patients suffering from long COVID and brain fog have impaired blood vessel integrity in their brains. The research team compared ``patients with long COVID with brain fog or cognitive decline confirmed'' and ``patients with long COVID but without symptoms of brain fog,'' and compared cerebrovascular disease. They reported that they were able to objectively distinguish between the two groups based on the presence or absence of bleeding.

Scientists and neurologists at Trinity College's Smurfit Institute of Genetics conducted a new MRI study that shows how the coronavirus affects the human brain's delicate network of blood vessels. Taking a scan.

Professor Matthew Campbell, director of the Smurfit Institute of Genetics and principal investigator at FutureNeuro, said: ``Bleeding from human brain vessels, in conjunction with an overactive immune system, may be linked to long-lasting coronavirus infections.'' For the first time, we were able to show that brain fog may be a major cause of brain fog. Understanding the root causes of these symptoms could lead to the development of targeted therapies for patients in the future. 'I will.'



The research between Trinity College and FutureNeuro was started using a grant funded by Science Foundation Ireland during the 2020 coronavirus pandemic. Subjects in the study included patients suffering from Long COVID and those admitted to St. James's Hospital.

Professor Colin Doherty, Dean of Medicine at Trinity College and principal investigator at FutureNeuro, who worked on the study, said: 'This complex clinical challenge came at a time when hospital systems were under severe pressure during a national crisis. It is a testament to the skills and resources of our residents and staff that we were able to carry out the study. This discovery could change the landscape of how we understand and treat neurological conditions following viral infection. 'We also confirmed that the neurological symptoms of Long COVID can be measured by real and demonstrable metabolic and vascular changes in the brain.'

in Science, Posted by logu_ii