Researchers claim that picking your nose may increase your risk of Alzheimer's disease



There are various factors that increase the risk of developing

Alzheimer's disease , such as eating too much junk food and not getting enough sleep . A review by a research team at Western Sydney University in Australia explains the mechanism by which ``nose picking'' may increase the risk of Alzheimer's disease.

Biomolecules | Free Full-Text | Neuroinflammation in Alzheimer's Disease: A Potential Role of Nose-Picking in Pathogen Entry via the Olfactory System?
https://www.mdpi.com/2218-273X/13/11/1568



Scientists Reveal How Nose-Picking Could Increase Risk of Alzheimer's : ScienceAlert
https://www.sciencealert.com/scientists-reveal-how-nose-picking-could-increase-risk-of-alzheimers

At first glance, the idea that picking your nose increases your risk of developing Alzheimer's disease, which causes cognitive and memory decline, seems like a myth or a hoax. However, the research team is scientifically examining the hypothesis that bacteria and viruses attached to fingertips enter the body through the nose and have a negative impact on the brain.

When scent molecules stimulate olfactory receptors in the human nose, the stimulation is transmitted to the olfactory bulb located at the top of the nasal cavity and below the frontal lobe . These olfactory systems have direct pathways to brain regions such as the hippocampus that are affected by Alzheimer's disease.

When you pick your nose with your fingers, pathogens attached to your fingertips are pushed toward your brain. Furthermore, by pulling out what's inside your nose, the balance of microbiota in your nasal cavity may change, weakening your body's barrier against pathogens. This is said to increase the risk that viruses and bacteria attached to fingertips will enter the brain through the olfactory system.

The research team said, ``Many factors are thought to be involved in the onset of Alzheimer's disease, including the deposition of amyloid-β and tau proteins , but recent evidence suggests that neuroinflammation may also be partially involved. 'In recent years, research has emerged that explores the possibility that invasion of external pathogens may be involved in the initiation or acceleration of the neuroinflammatory process in Alzheimer's disease.' In other words, the research team claims that picking your nose allows pathogens to enter the brain, and the resulting neural inflammation may increase the risk of Alzheimer's disease.

A 2022 study conducted on mice showed that the bacterium Chlamydia pneumoniae , which actually causes chlamydia pneumonia, travels through the olfactory nervous system and causes inflammation in the cranial nerves, causing amyloid-β deposits.



The research team also cited the fact that herpesviruses and other bacteria are commonly detected in the brains of Alzheimer's disease and dementia patients as evidence supporting the hypothesis that ``nose picking increases the risk of Alzheimer's disease.'' I am.

Furthermore, the fact that the first signs of Alzheimer's disease appear in the form of ``loss of smell'' suggests that the olfactory system is related to the risk of Alzheimer's disease.

Loss of smell may be an early sign of Parkinson's disease and Alzheimer's disease - GIGAZINE



This study merely reviewed various research results and predicted a link between nose picking and the risk of developing Alzheimer's disease, and did not prove a definitive conclusion. Still, the research team says, 'Understanding the potential role of pathogen entry through the sense of smell in the neuroinflammation associated with Alzheimer's disease opens new avenues for prevention. 'As we learned from the COVID-19 outbreak, improving hand hygiene may be an easy prevention step among all entry points,' he said, adding that the findings could help prevent Alzheimer's disease. I had high hopes.

in Science, Posted by log1h_ik