As a result of research that ``Western-style diet'' is a risk of Alzheimer's disease, food and supplements important for preventing dementia are also found



At the time of writing the article, about 25 million people with dementia are increasing year by year and are estimated to reach at least 115.4 million by 2050, but Alzheimer's disease, the most common type of dementia The exact cause is unknown and there is no effective treatment. Chinese researchers have announced that the risk of developing Alzheimer's disease may be related to a diet that tends to be high in sugar and fat.

Frontiers | Effect of nutrition in Alzheimer's disease: A systematic review

https://doi.org/10.3389/fnins.2023.1147177

Western Diet Identified as Risk Factor For Alzheimer's Disease, Scientists Warn : ScienceAlert
https://www.sciencealert.com/western-diet-identified-as-risk-factor-for-alzheimers-disease-scientists-warn



Research on Alzheimer's disease is actively carried out around the world, and although the cause has not been fully investigated, several studies have shown that diet and lifestyle may be deeply involved in the onset of Alzheimer's disease. I'm here.

Therefore, a research team led by Zhejiang University of Traditional Chinese Medicine Inmaculada Shu Lou et al. conducted

a systematic review to analyze the relationship between diet and nutrition and Alzheimer's disease from previous research published in the five years from 2018 to 2022. I did.

The research team searched four medical literature databases for literature on Alzheimer's disease and diet, and after excluding animal studies and trial data of specific drugs, the results were 17 randomized clinical trials and 21 systematic reviews and meta-analyses . A total of 38 items were found.



An analysis of these studies found that Western dietary patterns were a risk factor for mild to moderate Alzheimer's disease. The research team found that the Western-style diet, which is high in saturated fatty acids, sugar, and salt, puts extra stress on the human body, which causes the accumulation of

amyloid beta and tau protein in the brain, which causes dementia. I'm assuming it's linked to destruction.

While a Western diet increased the risk of Alzheimer's disease, we also found a diet that may prevent the development of mild to moderate Alzheimer's disease. These are the Mediterranean diet and the ketogenic diet .

The Mediterranean diet is a traditional Italian and Greek diet centered on whole grains, vegetables, fruits, and seafood, while the ketogenic diet is a diet characterized by avoiding carbohydrates and consuming large amounts of fat. is. However, the long-term ketogenic diet, which is an extreme diet, may pose other health risks, so the research team says that supervision by a professional nutritionist is essential when practicing.

In a paper, the research team said, ``Studies show that continuing a Mediterranean diet is associated with a 20% reduction in the risk of dementia.In addition, the ketogenic diet suppresses oxidative stress and inflammation, It may also be effective in treating Alzheimer's disease, as it has been shown to reduce the adverse effects of altered glucose metabolism in humans.'



Besides diet, omega-3 fatty acid and probiotic supplements have also been shown to be protective factors for Alzheimer's disease. According to the research team, proper intake of omega-3 fatty acids, especially eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are abundant in seafood and nuts, can slow the decline of cognitive function and prevent Alzheimer's disease. It is possible to reduce the risk. Probiotics are also important, as Alzheimer's patients have altered gut microbiomes that have been shown to exacerbate inflammation and impact cognitive function.

In the paper, the research team said, ``Nutritional interventions have been shown to slow the progression of Alzheimer's disease, improve cognitive function, and improve the quality of life (QOL) of patients. There are many shortcomings and gaps in knowledge, so more in-depth research is needed on the link between nutrition and Alzheimer's disease.'

in Science,   Junk Food, Posted by log1l_ks