Mar 24, 2021 10:50:00

'Ordinary cold virus' turns out to destroy the new coronavirus

As a result of an experiment in which cultured human cells were simultaneously infected with the new coronavirus (SARS-CoV-2) and

rhinovirus, which is said to be a typical causative virus of colds, 'the presence of rhinovirus is SARS-CoV-2. It turns out that it inhibits replication. ' New discoveries about virus-to-virus interactions are expected to further advance control of the new coronavirus infection (COVID-19).

Human rhinovirus infection blocks SARS-CoV-2 replication within the respiratory epithelium: implications for COVID-19 epidemiology | The Journal of Infectious Diseases | Oxford Academic
https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiab147/6179975

University of Glasgow --University news --Infection with common cold might provide some protection against COVID
https://www.gla.ac.uk/news/headline_781603_en.html

Rhinovirus is one of the typical causative viruses of colds, and since it grows only at a temperature of 33 degrees Celsius, it is said to infect only cells in the upper respiratory tract. Previous studies have shown that the interaction of rhinovirus with other respiratory viruses affects the severity of the infection and how it spreads, but with SARS-CoV-2. The effect remained unknown.

Therefore, a research team led by Professor Pablo Murcia of the University of Glasgow, England, inoculates human respiratory cells with SARS-CoV-2 and rhinovirus at the same time and cultivates them, and SARS-CoV-2 proliferates. I conducted an experiment to observe. As a result, SARS-CoV-2 decreased sharply and became completely undetectable after 48 hours. This tendency was similar even when SARS-CoV-2 was administered 24 hours after the infection with rhinovirus. Furthermore, even if rhinovirus is administered 24 hours after being infected with SARS-CoV-2 first, SARS-CoV-2 decreases sharply immediately after the administration of rhinovirus and disappears immediately. It is said that it has been done.

Regarding this result, Professor Murcia said, 'This study revealed that rhinovirus

induces the innate immune response of human respiratory cells and blocks SARS-CoV-2 replication. The immune response caused by infection with a virus that causes mild cold provides temporary protection against SARS-CoV-2, which can prevent SARS-CoV-2 infection and suppress the aggravation of COVID-19. It means that there is sex. '

Professor Murcia added, 'In the next stage of the experiment, we will study the virus-virus interactions identified this time at the molecular level to gain a deeper understanding of the effects of this phenomenon on COVID-19. We hope to apply our findings to develop strategies to combat COVID-19 and control infections. Until then, the new coronavirus vaccine will be the best way to protect yourself from COVID-19. I'm sure, 'he said, motivating future research and at the same time re-emphasizing the effectiveness of the virus.