Studies show that immunity gained from vaccination with the new corona vaccine may last for years

A vaccine against the violent new coronavirus infection (COVID-19) has been developed and is being inoculated around the world. However, it is not clear how long the immunity to the new coronavirus (SARS-CoV-2) will continue even after vaccination.

A study conducted in collaboration with the National Institutes of Health has shown the possibility that 'if you get the mRNA vaccine, your immune response can last for more than a few years.'

SARS-CoV-2 mRNA vaccines induce persistent human germinal center responses | Nature

mRNA Vaccines May Pack More Persistent Punch Against COVID-19 Than Thought – NIH Director's Blog

COVID-19 vaccines such as Moderna and Pfizer use mRNA vaccines that make antibodies against the protein by injecting part of the genetic information that makes the protein of the virus and acquire immunity to the virus. I will. Studies have shown that both the Pfizer and Moderna vaccines are effective six months after the second dose.

Previous studies focused solely on antibodies have shown that 'immunity may not last long because antibodies can be lost in weeks or months.' However, in May 2021, Jennifer Dan and colleagues at the Lahoya Institute of Immunology published a study focusing on 'memory B cells, ' which are immune cells involved in the rapid production of antibodies. In this study, blood tests were performed on people who were actually infected with SARS-CoV-2, and as a result, infected people continued to retain immune-related cells even 8 months after infection with SARS-CoV-2. The result was that 'the immune cells that make antibodies are retained for a long period of time, so it may be possible to maintain immunity for a long period of time.'

Research reports showing that immunity to the new coronavirus lasts for more than 8 months are published one after another --GIGAZINE

Following the research by Dan et al., The University of Washington's Jackson Turner and colleagues conducted the study on COVID-19 vaccine recipients rather than SARS-CoV-2 infected individuals. We observed the major immune cells in the lymph nodes of the participants who received the Pfizer vaccine twice. Lymph node biopsies were performed 3, 4, 5, 7, and 15 weeks after the initial vaccination, and as a result, active reactions leading to the production of memory B cells and the like continued in the lymph nodes until 15 weeks later. There were no signs of slowing down. 'The immune response from vaccination is very robust and persistent, and this response can last for years,' Turner and colleagues said.

Francis Collins of NIH said, 'Turner's research raises new questions such as' what kind of reaction is occurring in the lymph nodes 'and' what kind of function does the T cell that commands B cells work? ' It's one of the hopeful studies that I raise, but hopes that the vaccine will last for a long time. '

in Science, Posted by log1p_kr