Moderna, which succeeded in developing a new corona vaccine, announced that it will develop an 'HIV vaccine'
Moderna Provides Business Update and Announces Three New Development Programs in Infectious Disease Vaccines | Moderna, Inc.
https://investors.modernatx.com/news-releases/news-release-details/moderna-provides-business-update-and-announces-three-new
Moderna to develop three new mRNA-based vaccines against HIV, influenza, and the Nipah virus
https://www.news-medical.net/news/20210113/Moderna-starts-to-develop-three-new-mRNA-based-vaccines-against-HIV-influenza-and-the-Nipah-virus.aspx
Moderna Is Developing an mRNA Vaccine for HIV | Freethink
https://www.freethink.com/articles/mrna-vaccine-for-hiv
The new coronavirus vaccine developed by Moderna hasshown high efficacy in clinical trials, and at the time of writing the article, inoculation has started in the United States and Europe .
In a statement on January 11, 2021, Moderna announced a program to develop new vaccines for the 'human immunodeficiency virus,' 'seasonal influenza virus,' and 'nipah virus.' AIDS and influenza are serious illnesses that affect millions of people each year and kill hundreds of thousands. Nipah virus infection is a zoonotic disease that exists mainly in Southeast Asia, and the case fatality rate of infected people is estimated to be 40 to 75%.
In a statement , Moderna CEO Stephane Bancel said, '2020 was a year of unparalleled challenge for society as a whole and a period of demonstration of a special concept for Moderna,' a vaccine for the new coronavirus. It is said that the great results of the development helped the new plan.
A vaccine is a vaccine that produces antibodies by administering an antigen to the body to promote immunity, and a detoxified or attenuated pathogen is generally used. The production of vaccines that utilize pathogens such as viruses requires careful work, and in the past, polio vaccines were contaminated with uninactivated viruses, and many children developed polio. ..
However, the vaccine developed by Moderna and Pfizer is an mRNA vaccine that uses mRNA that has the base sequence information that is translated into protein in the body, and does not use the original virus. Therefore, even if you are vaccinated against the new coronavirus, there is no risk of developing the new coronavirus infection (COVID-19) or infecting anyone with the new coronavirus by mistake.
The mRNA vaccine contains mRNA with the genetic information that produces 'only a part of the pathogen'. In the body of a person who receives the mRNA vaccine, the body acquires immunity by producing only the protein that is the antigen of the pathogen, but not the protein that causes the disease. In the case of the new coronavirus vaccine, only the spike protein , which is important when infecting human cells, is produced in the body, so even if vaccinated, there is no possibility of being infected with the new coronavirus.
Prior to the pandemic of the new coronavirus, the US Food and Drug Administration had never approved the mRNA vaccine, but in 2020 it urgently approved the new coronavirus vaccine from Moderna and Pfizer. This opened up the possibility of an easy-to-develop and expandable mRNA vaccine, which led Moderna to announce a new vaccine development plan.
The influenza, HIV virus, and nipavirus vaccines developed by Moderna are all mRNA vaccines, and it is planned to conduct Phase 1 trials (Phase 1) of influenza vaccine and HIV vaccine by the end of 2021.
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