First scientific evidence that irregular menstruation is associated with premature death risk



A 24-year survey of about 80,000 nurses living in the United States provided for the first time evidence linking irregular menstruation to premature death. People who experience irregular menstruation or prolonged menstrual cycles throughout puberty and adulthood are more likely to die by the age of 70. This association was prominent in the case of death associated with cardiovascular disease and cancer.

Menstrual cycle regularity and length across the reproductive lifespan and risk of premature mortality: prospective cohort study | The BMJ

https://www.bmj.com/content/371/bmj.m3464

Irregular Menstruation Was Just Linked to Early Death. Here's Why That's Important
https://www.sciencealert.com/large-study-suggests-irregular-periods-are-a-potential-sign-of-early-death

Menstruation is sometimes called the 'fifth vital sign ' following body temperature, pulse, breathing, and blood pressure, and is closely associated with diseases such as genital diseases, heart diseases, cancer, and mental illness. This does not mean that menstrual irregularities do not necessarily cause a particular illness, but that irregular menstrual periods are susceptible to poor health. For this reason, the findings that 'irregular menstruation is associated with premature death' are not surprising, but nonetheless, it is said that patients are rarely asked about their menstrual cycle during their examination. I will.

In response to the findings, King's College London reproductive physiologist Kim Jonas said, 'Hopefully, this study raises awareness of irregular menstrual cycles and evaluates health by both doctors and female patients. You may be encouraged to consider your menstrual cycle when you do. '



The survey, which began in 1989, was conducted on 80,000 nurses aged 25-42 years in the United States. The researchers sent letters and emails to the subjects every two years, asking them about their lifestyle, diet, medical history, and whether they had any illness. In the first survey in 1989, nurses were encouraged to remember their menstrual status when they were 14 to 17 years old and when they were 18 to 22 years old. After that, in a 1993 survey, he asked the same subject about his menstrual cycle as of 1993. The subject's age at this time was 29-46 years.

The menstrual cycle is usually 26 to 30 days, but studies show that people who had a menstrual cycle of 40 days or more when they were older were at higher risk of premature death than those who did not. Researchers note that the risk was especially high for people who have had irregular menstruation since puberty, and for smokers. Even considering factors such as weight, age, lifestyle, and family medical history, the research results did not change.

'It's important to remember that irregular menstruation is a symptom, not the disease itself,' said Jacqueline Mabin, a researcher at the University of Edinburgh. That is, the specific cause under irregular menstruation is irregular bleeding. Not only does it increase the risk of premature death. '



However, the survey targeted white female nurses, and it is possible that irregular working hours affected long-term health. Further research is needed to clarify the link between irregular menstruation and premature death, but because randomized trials are difficult for menstruation, this study understands the long-term health effects of the menstrual cycle. It is rated as a very valuable proof to do.

in Science, Posted by darkhorse_log