A paper device that detects new coronavirus from wastewater and stops the epidemic is under development



With the new coronavirus (SARS-CoV-2) rampant around the world, scientists are trying to combat pathogens using a variety of approaches. Zhugen Yang, a biomedical engineer at Cranfield University in the UK, has newly detected the presence of SARS-CoV-2 from the genetic material in wastewater, and found a place where the new coronavirus infection (COVID-19) is spreading. We are developing a device that can be identified.

Can a Paper-Based Device Trace COVID-19 Sources with Wastewater-Based Epidemiology? | Environmental Science & Technology

https://pubs.acs.org/doi/full/10.1021/acs.est.0c01174

Wastewater test could provide early warning of COVID-19
https://www.cranfield.ac.uk/press/news-2020/wastewater-test-could-provide-early-warning-of-covid-19

Scientists Are Developing a Test to Find The New Coronavirus in Wastewater
https://www.sciencealert.com/scientists-are-developing-a-test-that-can-find-the-new-coronavirus-in-wastewater



Because many asymptomatic patients exist for COVID-19, it is extremely difficult to identify where the virus is prevalent by the presence or absence of symptoms. Therefore, the research team of Yang et al. Has developed a mechanism that can detect SARS-CoV-2 in wastewater with a paper-based device.

The research team seems to have already developed a paper device at the proof of concept level, Mr. Yang said, `` This device is very cheap at less than 1 euro (about 117 yen), and if it is improved, it is easy even for non-experts We expect that with widespread availability of devices, we will be able to get a quick and complete picture of overall public health. '

Such research, called Wastewater-Based Epidemiology, is gaining attention as a new non-invasive method of collecting data in real time.

The device being developed by Yang and his colleagues is to detect pathogen nucleic acids from wastewater. Because paper devices contain chemicals, a green circle appears on paper when SARS-CoV-2 nucleic acids are detected, and a blue circle appears when they are not. Devices can be easily transported and stored, and can be burned after use, which is considered to be a small hurdle in distribution.



It has been pointed out that SARS-CoV-2 is spread through feces . Research published on March 5, 2020 showed that SARS-CoV-2 can remain active for several days in vitro after leaving the feces. Based on the results of this study, Yang believed that wastewater testing was effective.

The paper device is in the proof-of-concept stage, but it may actually work. This test will allow measures to be taken to minimize expansion in areas where SARS-CoV-2 has been detected in wastewater.

`` If there are no asymptomatic patients in the community or if you do not know if an infection is occurring, testing wastewater with such a paper device will help you to 'test, isolate, and take precautionary measures for COVID-19 in your area. Early monitoring of COVID-19 in the community through wastewater-based epidemiology will enable effective interventions, such as limiting local movement. It can minimize the spread of the virus and the threat to public health, 'said Yang.

in Science, Posted by logq_fa