It turns out that it is effective for part of cancer medicine to effectively link AIDS virus to death

ByNIAID

Destroy human immune system cells to deathAIDS(AIDS) has been considered a disease that is difficult to recover, but in recent research it is a virus that causes AIDSThe possibility that days will come when HIV is weakened and becomes almost harmlessI can see it. It is becoming clear that some anti-cancer drugs have the effect of dramatically enhancing the effect of drug treatment and eradication by hitting sleeping HIV in the body as if accelerating the flow further It was.

PLOS Pathogens: Synergistic Reactivation of Latent HIV Expression by Ingenol-3-Angelate, PEP005, Targeted NF-kB Signaling in Combination with JQ1 Induced p-TEFb Activation
http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1005066

HIV flushed out by cancer drug - BBC News
http://www.bbc.com/news/health-33720325

At the site of AIDS treatmentAntiretroviral drugTo suppress the proliferation of HIV by suppressing the proliferation of HIV has shown great effect, but this has been to stop the progress of the disease to the end, has not had the situation that it does not lead to complete recovery It was. In addition to this, HIV before activation is quietly hidden in the patient's body, and it is difficult to recover completely because it can not effectively take measures using drugs.

ByDepartment of Foreign Affairs and Trade

The research team of the University of California Davis announced,Article published in PLOS PathogensAccording to the research team, sunburn caused by drugs to suppress skin cancer caused by "PEP005"When I investigated a substance called" HIV, I was able to confirm the possibility of showing a great effect on revitalizing HIV who was hiding. "

As a countermeasure against HIV, "Kick and killThe method expressed as "promising" has been considered. It was a technique of killing HIV by kicking off HIV who was in a dormant state and hiding in the human body and killing HIV by administering medicine there. Whether to give "kick" is the key to this technique.

The research team confirmed its effect by giving this substance to cultured cells based on the immune system collected from 13 HIV-infected patients. In the paper on the result, "PEP005 has a high effect in activating dormant HIV", and this substance is said to occupy "a new group of substances playing a major role in fighting HIV" I will.

ByPlanet Earth

One of the research team, Dr. Satya Dandekar, said, "We found outstanding candidates for reactivation of HIV, and it is hard to find that medicine has already been found in drugs that are actually used in actual healthcare settings I am excited, "he says, expressing expectations for great help in this research.

Although the finding that possibly dramatically improves treatment of AIDS was revealed, the future task is the verification work on HIV positive patients. Professor Sharon Lewin of the University of Melbourne commented, "According to the results of this research, a new group will be added to drugs that could potentially control HIV," he says, "PEP005 is a FDA approved drug However, we still need some time to confirm the safety as an HIV drug against the drug, "he says of verification work required in the future.