It turns out that sleep deprivation causes memory loss and it also accumulates proteins that form the basis of Alzheimer's

ByAsim Bharwani

Insufficient sleep time for recovery of physical fitness causes memory disorder and Alzheimer's diseaseAmyloid β proteinTo accumulate in the bodyUniversity of California, BerkeleyBrain scientists discovered. The discovery of this time seems to be a clue to elucidate Alzheimer's disease which is still encompassed in mystery.

Sleep Deficit Linked to Accumulation of Alzheimer's Protein and Memory Loss | Neuroscience News

Mr. Matthew Walker, a brain scientist who carried out the research, said in a paper published in Nature Neuroscience, "Alzheimer's disease has found a link to cause memory loss." In the past study on Alzheimer's disease studies, it is known that excessive accumulation of amyloid β protein is the main source of the disease, but this time when newly deep sleep for recovery of fatigue is insufficient, long-term memory of the brain It has been found that amyloid β protein, which triggers Alzheimer's disease, is affected.

William Jagust, a co-researcher and leader in Alzheimer's disease at the University of California at Berkeley, said, "In the past few years studies, sleep, amyloid β protein, memory, Alzheimer's disease are more closely linked However, in this study, it turned out that sleep became shallow as amyloid β protein went round, and it also proved to have an effect on memory, "he says.

For example, in a mouse experiment conducted in Rochester University in New York in 2013, mouse brain cells shrink during non-REM sleep, and harmful substances in the brain, including amyloid β protein, are allowed to flow out Being creating spaceI know. In addition, during non-REM sleep, memory moves from the hippocampus, which controls short-term memory, to the prefrontal cortex which incorporates long-term memory, but it also turned out that sleep deprivation was caused by the decline of the prefrontal cortex as age It was.

ByDenise Chan

The experiments conducted in the past were mainly for animals, but this time the experiment was conducted for healthy people aged 65 to 81 years, after remembering 120 words for 8 hours I got a good night's sleep. The next morning when I scanned my brain using fMRI, the prefrontal cortex was activated more than the hippocampus of the brain when trying to remember the word. People who had a high value of amyloid β protein had poor sleep quality, and the number of words remembered was also very low, being less than half.


Walker says, "The more amyloid β protein accumulates, the lower the quality of sleep, the lower the memory ability, and furthermore, if you do not have a deep sleep, you can kill harmful substances such as amyloid β protein from within your brain It becomes a vicious circle that it becomes difficult, "he says.

Sleep deprivation is a moderate exercise andBehavior TherapyImprovement by electrotherapy, when we conducted an experiment to actually flow fine electric current to sleeping brain, improvement seems to be improved in the memory ability the next morning happened. Walker also says sleep therapy can be used to treat the elderly who have been diagnosed with dementia or Alzheimer's disease, says Mr. Walker, which says that sleep can often suppress memory disturbance.

ByAnoop & amp; Shraddha Iyer

Researchers at the University of California at Berkeley will continue to research therapeutic methods for Alzheimer's disease and memory impairment for elderly patients over the next five years.

in Science, Posted by darkhorse_log