Research results show that sulforaphane, a cancer-preventing ingredient found in broccoli, also prevents stroke.



Cruciferous vegetables such as broccoli, cauliflower, and broccoli sprouts contain a compound called

sulforaphane . This sulforaphane is thought to be effective in preventing cancer and lowering cholesterol, but a research team at the University of Sydney in Australia has newly found that it may also be useful in preventing stroke. announced.

Integrating Phenotypic and Chemoproteomic Approaches to Identify Covalent Targets of Dietary Electrophiles in Platelets | ACS Central Science
https://pubs.acs.org/doi/full/10.1021/acscentsci.3c00822

Broccoli's Anti-Cancer Compound Could Have a Whole Other Health Benefit : ScienceAlert
https://www.sciencealert.com/broccolis-anti-cancer-compound-could-have-a-whole-other-health-benefit



Common veggie could help prevent and treat stroke

https://www.hriuk.org/news/common-veggie-could-be-secret-weapon-to-treat-stroke

Platelets, a blood component, play an important role in sealing wounds and stopping bleeding, but under certain circumstances, platelets can become stuck and form dangerous blood clots that completely block blood flow. You may. When a blood clot forms in a vital tissue such as the brain or heart, oxygen cannot be circulated to the tissue, resulting in a life-threatening situation.

Sulforaphane, which is found in large amounts in cruciferous vegetables such as broccoli, is known to have anticoagulant properties and has attracted attention for its various health benefits, including cancer prevention. The research team analyzed sulforaphane at the molecular level and showed that by promoting the activity of a protein called PDIA6, it may be able to slow platelet aggregation and inhibit blood clot formation under conditions similar to those in arteries.

'The sulforaphane contained in broccoli is not only effective in improving the effectiveness of blood clot-busting drugs in stroke patients, but also as a preventive drug for patients at high risk of stroke,' said research team member Liu Shu. It may be possible to use it.”



The analysis shows that sulforaphane may also be useful for patients who have had a stroke and are in critical need, where the effects on the brain are immediate. In addition, while

tissue plasminogen activator (tPA), a conventional blood clot-busting drug, had a 20% chance of being effective in preventing brain damage, the combination of sulforaphane and tPA showed that effect. It turns out that the probability can reach up to 60%.

Furthermore, Ryu reports, ``Interestingly, the side effect of ``making it difficult to stop bleeding,'' which is often seen with drugs that thin the blood, was not observed in experiments using sulforaphane.''



In Australia, 55,000 people are born with stroke each year and approximately 23 people die each day. 'A breakthrough in stroke prevention using sulforaphane could pave the way to the development of new, life-saving drugs,' said Liu. 'We were able to analyze a compound that could have significant beneficial effects. I'm happy about that.'

Please note that this research is in its early stages and has not been tested on humans. Ryu said, ``We plan to verify in future research whether simply eating broccoli can reduce the risk of stroke.''

in Science,   Junk Food, Posted by log1r_ut