It turns out that the brain becomes aged for 1 to 2 years just by staying up all night



There must be many people who have been immersed in work, study, or hobbies without even sleeping. But studies have shown that staying up all night can make your brain look like it's aged one to two years overnight.

Total sleep deprivation increases brain age prediction reversibly in multi-site samples of young healthy adults | Journal of Neuroscience

https://doi.org/10.1523/JNEUROSCI.0790-22.2023

Human brain looks years 'older' after just one night without sleep, small study shows | Live Science
https://www.livescience.com/human-brain-looks-years-older-after-just-one-night-without-sleep-small-study-shows

A research team led by David Elmenhorst of Rhein-Friedrich-Wilhelm University Bonn divided 134 participants into ``all-night group'', ``3-hour sleep group'', ``5-hour sleep group'', ``8 They were divided into 4 groups of 'time sleep group' and MRI of the brain was taken.

After that, the research team used a machine learning algorithm ' brainageR ' learned based on MRI images of more than 3000 people to estimate the brain age of the participants. brainageR is an algorithm that predicts brain age estimates in presented brain MRI images in terms of brain tissue and fluid volume based on learned data.

The brain age of the group of participants who stayed up all night was determined by brainageR to be on average 1-2 years older than the group who slept 8 hours. Also, when the group that stayed up all night got enough sleep again, the aging of the brain returned to the same state as the group that slept 8 hours.



However, when comparing the 3-hour sleep group and the 5-hour sleep group with the 8-hour sleep group,

no significant difference was found in brain age prediction by brainageR.

It is said that various changes occur in the brain of sleep deprived people, such as changes in the distribution of body fluids and the amount of gray matter . The results of the research by this research team are consistent with previous research on the effects of sleep deprivation on the brain.

Mr. Elmenhorst says, `` Brain aging due to staying up all night is not actually aging, but brainageR judged aging. Furthermore, 'the long-term effects of chronic sleep deprivation could not be clarified in this study.'



``The number of participants in this study was relatively small, 134,'' Elmenhorst said. I want to do it,' he said.

in Science, Posted by log1r_ut