Detailed distribution of 'Neanderthal DNA' that increases the risk of aggravation of the new corona is revealed


study published in July 2020 revealed that Neanderthal genes may be responsible for the aggravation of the new coronavirus infection (COVID-19). A more extensive study of people with the Neanderthal-derived genes identified at this time revealed a detailed distribution of people with risk factors for the aggravation of coronavirus infection.

The major genetic risk factor for severe COVID-19 is inherited from Neanderthals | Nature

The aggravation of the new corona was inherited from Neanderthals | Okinawa Institute of Science and Technology Graduate University OIST

Hugo Zeberg, a neurologist at the Karolinska Institute in Sweden, and Svante Pääbo, a technician at the Max Planck Institute for Evolutionary Anthropology in Germany, said in July 2020, 'Neanderthals on chromosome 3 of modern humans. Gene is closely related to the aggravation of COVID-19. ' Ironically, it was revealed that a Neanderthal gene, which was once said to have helped boost immunity to another infectious disease, has exacerbated COVID-19.

It is possible that the DNA that humans inherited from Neanderthals 60,000 years ago is associated with 'aggravation of the new coronavirus infection' --GIGAZINE

by Erich Ferdinand

Zeberg and colleagues identified DNA from Neanderthals that exacerbated COVID-19, and then examined the distribution of the DNA in question from the 1000 Genomes Project, an international project to investigate genetic diversity.

The map below shows the results. The pie chart shows the percentage of people living in the area who carry the Neanderthal gene, which is at risk of aggravating COVID-19.

Regarding this result, Pääbo said, 'The Neanderthal genes found in this area may have protected Neanderthals from other infectious diseases that do not exist in modern times. And we face COVID-19. Now that these Neanderthal genes have tragic consequences, 'he said.

In a paper by Zeberg et al., 'It is impressive that about 30% of people in South Asia carry the Neanderthal aggravation risk gene, while it is rarely found in East Asia. It is. ' In particular, Bangladesh has the highest proportion of people with genes at high risk of aggravation, with about 63% of the population carrying the gene in question.

'People with the Neanderthal-derived COVID-19 aggravation risk factor we identified triple the risk of needing a ventilator when infected with COVID-19, of course. Age and other illnesses also affect aggravation, but this gene is the strongest genetic factor. '

in Science, Posted by log1l_ks