Report that new coronavirus infection causes 'thrombus in major organs such as heart, lungs and kidneys'

After dissecting a patient who died of a novel coronavirus infection (COVID-19), a research result was announced that 'a blood clot was found in major organs such as the heart, lungs and kidneys.'

Megakaryocytes and platelet-fibrin thrombi characterize multi-organ thrombosis at autopsy in COVID-19: A case series-EClinicalMedicine
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(20)30178-4/fulltext

Coronavirus autopsies: Small vessel blood clotting found in patients, pathologist says-CNN
https://edition.cnn.com/2020/07/10/health/what-coronavirus-autopsies-reveal/index.html

Autopsies Indicate Blood Clots Are Lethal in COVID-19 | The Scientist Magazine®
https://www.the-scientist.com/news-opinion/autopsies-indicate-blood-clots-are-lethal-in-covid-19-67727

On July 10, 2020, a research team headed by Amy Rapkiewicz, director of the Department of Pathology at the Langone Medical Center in New York University, published a study showing that blood clots have spread to minute blood vessels. When the research team dissected 7 patients (4 of whom were female) who died of COVID-19, all autopsies confirmed thrombi containing many platelets in minute blood vessels such as lungs, liver, kidneys, and heart. That.

In addition, cells called ' megakaryocytes ', which play a role in producing platelets, were also found in organs such as the heart, kidneys, and liver, which would not normally circulate. “It's possible that megakaryocytes produced platelets in the heart, which could have led to blood clotting,” Rapkiewicz said.

'The lungs were as expected, but we were able to find blood clots in almost every organ except the lungs examined at necropsy,' said Rapkiewicz.

Initially, COVID-19 was reported to be a 'pulmonary disease like pneumonia'. However, as the damage spreads and research progresses, it has become clear that it may affect various parts of the body such as the brain . It has been pointed out that within each part of the body, 'blood and blood vessels' may also be damaged by the new coronavirus.

Patients who become severe due to new coronavirus infection may have major problems with ``blood''-GIGAZINE

'At COVID-19, blood clots can kill lives,' said Sigurd Lax, an authority on Austrian pathology at Graz Medical University, on July 10, 2020. He explained from a number of autopsies that inflammation of blood vessels and the tendency of blood to coagulate could lead to blockage of the pulmonary arteries, eventually leading to heart failure.

As a countermeasure for such blood coagulation, anticoagulation therapy is being carried out for new coronavirus-infected persons. The Japanese Society for Vascular Surgery also said, 'COVID-19 is prone to thrombotic diseases in both arterial and venous systems due to excessive inflammation, platelet activation, endothelial dysfunction, and congestion' Recommends anticoagulant therapy for patients undergoing antithrombotic therapy for thrombotic disorders.

However, Professor Lax noted that he had 'provided a prophylactic level of anticoagulant to prevent blood clotting,' for patients who died due to pulmonary arterial thrombosis caused by COVID-19, 'and still said It was not enough to prevent the disease.'