Rebuttal that there is also an environmental influence on research that the main cause of cancer is "bad luck"

ByChristopher Craig

In January 2015, "In the midst of 2015," the majority of causes of cancer are not genetic or environmental factors, but mutation occurs in genes that promote tumor growth "It was published in Science magazine · ScienceHowever, an objection that there are many environmental factors against this was announced in the scientific journal · Nature.

Substantial contribution of extrinsic risk factors to cancer development: Nature: Nature Publishing Group
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature16166.html


Cancer studies clash over mechanisms of malignancy: Nature News & amp; Comment
http://www.nature.com/news/cancer-studies-clash-over-mechanisms-of-malignancy-1.19026


Cancer is not just 'bad luck' but down to environment, study suggests - BBC News
http://www.bbc.com/news/health-35111449

In the research paper published in Science in January 2015 "While one can account for the cause by a random mutation that occurs in a gene that promotes tumor growth, the remaining one third was due to environmental factors and genes inherited from the parent"Most of the cancer is due to" luck ", people with a smoking habit or taking a lot of sunlight, who live longer without cancer become" I am explaining that "Because I'm in luck" instead of "not being".

However, according to the paper published in Nature this time, an endogenous risk factor such as "a random mutation in a gene that promotes the growth of a tumor" which was expressed as "lucky" in the previous paper is It is about 10 to 30% that contributes to the occurrence, and the big one is external factors such as the environment.

One of the authors Dr. Yusuf Hanun is a parable using a revolver-type pistol, the internal factor is like a single bullet and the smoker seems to put 2 or 3 bullets Explain that it is something. When doing Russian roulette, bullets are not necessarily fired, so we acknowledge the elements of luck certainly. However, not all external factors are recognized, it says that the problem still remains, as it does not necessarily have a means to avoid like chemicals and radiation.

Edward Giovanucci, who studies cancer prevention at Harvard TH Chan School of Public Health, said in a paper published in Science that "cancer is mainly due to bad luck and efforts to prevent is not beneficial" Because there is a possibility that it is possible, there are cancer prevention experts who welcome papers published by Nature.

It is clear that there are cancers that are strongly linked to environmental factors, such as liver cancer caused by hepatitis C infection or lung cancer due to smoking, but cancer that is not so is a factor of "bad luck" Whether it is big or not, it may be more clearly understood if research proceeds.