It is announced that there is a possibility that days when HIV is weakened and "almost harmless" will come


ByNIAID

HIV has been considered difficult to cure so far, but recent research has found that the fatality rate and infection rate by HIV have declined. BBC summarizes the current situation of HIV that "the virus is getting in a mild form".

Impact of HLA-driven HIV adaptation on virulence in populations of high HIV seroprevalence
http://www.pnas.org/content/early/2014/11/26/1413339111

BBC News - HIV evolving 'into milder form'
http://www.bbc.com/news/health-30254697

According to the team of the Oxford University who conducted the research, HIV is "in a mild form", HIV is getting longer time to cause AIDS,PandemicIt is said that the likelihood that it will cause is also decreasing. Some researchers say that "There may be days when HIV becomes almost harmless as it is," some of them are.

There are 35 million HIV-infected people in the world, and in the body of infected people, the battle between the virus and the immune system will be fought. HIV immediately adapts itself to the infected person's immune system, but rarely the body's immune system is powerful and adaptation can take time.

At this time the virus can not move and will change itself to survive, but it will be a burden to change. This burden is "reduced replication ability", which lowers the infection rate of viruses and lengthens the time to cause AIDS. And the weakening cycle is born by the weakened virus being transmitted from person to person.

ByEMSL

HIV has been a serious problem for many years in Botswana, but the research team compares HIV spread in Botswana and HIV epidemic in South Africa about 10 years after the epidemic in Botswana, weakening HIV Respectively.

Professor Golder who researched responded to BBC 's interview that the Botswana virus had a 10% lower replication capacity than the South African virus. "We saw a change in the virus, but this change occurred at a surprisingly fast speed, a decline in the ability of the virus to replicate will help eliminate the presence of the virus itself," Professor Golder said I am talking.

further,Reverse transcriptasehaveRNA virusSomething ofRetrovirusHIV belongs to this retroviridae, but according to the findings of the National Academy of Sciences, antiretroviral drugs also make HIV mild form. Antiretroviral drugs suppress the growth of the virus in the body and suppress the onset of AIDS and were made for the type of HIV considered to be the most dangerous.

"The time from infection with HIV in Botswana to the onset of AIDS in Botswana was 10 years ago, but in the past 10 years the period has been extended to 12.5 years.When this increases steadily, the future HIV infected people will be able to live for decades without causing AIDS, "said Professor Golder.

ByGates Foundation

However, even the weakened HIV does not change that it is dangerous, and the research team also warns that there is a sufficient possibility of developing AIDS.

Although HIV is thought that simian immunodeficiency virus (SIV) has infectivity to humans by mutation, infection rate was originally low. Professor Jonathan Ball, a virologist at the University of Nottingham, said on the weakening of the virus: "If this trend continues, the situation on HIV will change globally, hypothesizing, but to the weakening of HIV There is also the possibility that human beings who are more resistant to viruses than we are today may come out, so that HIV is almost harmless. " Although it may sound optimistic, it seems that there is a possibility that the above events actually occurred in history.

Meanwhile, Professor Andrew Friedman at Cardiff University "This study, which demonstrated that the infectivity is weakening by comparing HIV spread in Botswana and HIV spread in South Africa is very interesting. It is said that anti-retroviral therapy spreads and time to the onset of AIDS has been extended, and it can be said that it controls HIV spreading, "while taking a positive position, until the virus becomes harmless "It takes a horribly long time," he said. Rather than weakening the virus itself, it seems that days of HIV becoming a past illness are close by the development of therapy and generalization of medical care.

ByMani Babbar Photography

in Science, Posted by darkhorse_log