So that a man who has become ``allergic to his own semen'' can ejaculate with peace of mind with doctor's treatment



There are various allergies in the world, and although it is very rare, there are cases where allergic reactions are caused to 'own semen'. In a case published in the medical journal Urology Case Reports, a man who suffered from various symptoms after ejaculation was reported to be able to ejaculate safely again with the treatment of a doctor.

Post orgasmic illness syndrome successfully managed with antihistamine: A case report - ScienceDirect

https://doi.org/10.1016/j.eucr.2022.102189

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https://www.zmescience.com/science/orgasm-allergy-common-antihistamines-treatment-92462452/

A 27-year-old man featured in the case report visited a hospital complaining that 'after ejaculation, symptoms such as coughing, runny nose, sneezing, and forearm hives appear.' Symptoms complained by men appeared with ejaculation regardless of whether it was masturbation or sex, and these symptoms led men to avoid aggressive sexual and romantic activities.

It seems that the male symptoms began when he was 18 years old when he suffered from acute epididymitis caused by bacteria invading the vas deferens from the urethra. I have visited multiple medical institutions, including urology, otolaryngology, infectious diseases, and allergy, but my symptoms have not improved.



When I visited the urology department of

William Beaumont Hospital , where I presented this case, the doctor diagnosed me with a syndrome called ' postorgasmic illness syndrome (POIS) ,' in which chronic physical and cognitive symptoms appear after ejaculation. did.

POIS is a disease in which flu-like symptoms such as malaise, fever, mood disturbance, memory impairment, lack of concentration, and stuffy nose appear immediately after ejaculation, and most symptoms occur about 2 to 7 days after ejaculation. It will disappear naturally. POIS is a rare disease with fewer than 60 cases reported in the literature worldwide since the first case was reported in 2002, but the potential number of patients is thought to be much higher.

It is unknown what causes POIS, but based on clinical symptoms and the results of allergy tests, the hypothesis is that it is an ``allergic reaction to one's own semen''. Normally, people do not have an allergic reaction to their own semen, but it is thought that there are cases in which the immune system recognizes the compound contained in the semen as a foreign substance and attacks it due to external factors such as sterilization surgery. In this case, it is possible that the acute epididymitis that the man had when he was 18 years old triggered POIS.

Due to the small number of cases of POIS, no clear treatment method has been established, but doctors started treatment with antihistamines , which are general allergy medicines. After testing several candidates, I found that a daily dose of fexofenadine , also known as Allegra, was effective. It is reported that taking fexofenadine reduced post-ejaculation symptoms by 90%, allowing men to resume sexual activity again.



in Science, Posted by log1h_ik