Austrian University Develops Vaccine for All New Coronaviruses, Including Omicron Strain
The University of Medical Sciences in Vienna, Austria, announced that it has developed a vaccine ' PreS-RBD ' that is effective against all new coronaviruses including the Omicron strain.
Vaccine based on folded RBD-PreS fusion protein with potential to induce sterilizing immunity to SARS-CoV-2 variants --Gattinger ---- Allergy --Wiley Online Library
Corona: PreS-RBD-Impfstoff von MedUni Wien könnte vor Omikron schützen --Corona-Impfung --VIENNA.AT
https://www.vienna.at/corona-pres-rbd-impfstoff-von-meduni-wien-koennte-vor-omikron-schuetzen/7358236
New Austrian Covid-19 vaccine could protect against Omicron
https://www.thelocal.at/20220405/new-covid-19-vaccine-from-austria-could-protect-against-omicron/
Newly developed COVID vaccine could protect against omicron and other variants
https://medicalxpress.com/news/2022-04-newly-covid-vaccine-omicron-variants.html
The PreS-RBD, newly developed by Rudolf Valenta and colleagues at the University of Vienna, targets the 'infectious receptor binding site (RBD),' which is the site that the new coronavirus directly binds to when infecting human cells. A vaccine that inhibits the infection itself. In animal and human studies that have already been conducted, it has been confirmed that a long-lasting IgG antibody reaction appeared strongly and uniformly.
PreS-RBD has also been shown to be effective against Omicron mutants , which have been pandemic since the end of 2021, and the virus antibody titer, which is the effectiveness of the vaccine, is that of people who have been vaccinated twice with existing vaccines and COVID-. It was higher than the value of 19 recoverers.
In addition, PreS-RBD has a 'PreS antigen' used for hepatitis B vaccine, which enables cooperation with T cells , which are the control tower of immune action. According to Valenta et al., It will also bring antibodies to people who are infected with COVID-19 but do not produce anti-RBD antibodies (about 20% of those who have recovered from the new coronavirus).
The safety of PreS-RBD has also been confirmed in human studies so far, Mr. Valenta said, 'This vaccine is designed to build continuous sterile immunity by repeated injections. It can be used by all age groups and risk groups and is considered superior to existing vaccines in inducing neutralizing antibodies. '
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