Research results show that 'just being bitten by a mosquito' has a great effect on the immunity of the human body
When a mosquito bites a person, it injects saliva to prevent blood from clotting before sucking, which can cause itching for days. In addition, experiments in which mosquitoes suck the blood of mice transplanted with human hematopoietic cells have shown that mosquito saliva has more effects than itching.
Mosquito saliva alone has profound effects on the human immune system
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Mosquitoes are sometimes referred to as the 'most killing creatures ' because mosquito-borne infections kill 750,000 people worldwide each year. In addition, previous studies in mice have shown that mosquito bites and infections are at higher risk of becoming more severe than inoculating the pathogen with a needle.
natural killer cells , natural killer T cells , CD8 + T cells , monocytes , and macrophages , which are a type of helper T cells , undergo an immune response when bitten by a mosquito. I found out. In addition, the immune response was confirmed in various parts of the body tissue such as skin, blood, and bone marrow, and it continued to be detected for 7 days after being stabbed.
Therefore, a research team led by Professor Rebecca Rico Hesse of the American Baylor Medical University conducted an experiment to reproduce the immune response of a mosquito bite using mice transplanted with hematopoietic stem cells involved in the human immune system. I did it. Specifically, after biting the soles of the mice's feet with four mosquitoes, the number of immune cells and the status of activation were examined. In the experiment, mosquitoes that did not have any infectious disease were used.
As a result of this experiment, various cells such as Th1 cells, Th2 cells,
Regarding this result, the research team said, 'The mechanism by which the immune response after being bitten by a mosquito was detected for a long time has not yet been identified. It may support the finding that pathogens such as the virus that have been infected may spread throughout the body and remain in the body tissue for a long period of time. '