British mutants of the highly infectious new coronavirus are acquiring mutations that reduce vaccine efficacy

British researchers, 'is also a' strong infectivity 'in the new coronavirus mutant strain has been confirmed many

B.1.1.7 case that it is', won a mutant of the spike protein 'E484K' Announced that it has confirmed at least 15 cases. Peplomers are located on the surface of the new coronavirus and bind to human receptors to help mediate the virus. One of the mutations in this spike protein, 'E484K,' has been found to reduce the effectiveness of Pfizer vaccines by about one-tenth , and B.1.1.7, which is originally highly infectious, acquired E484K. Doing so may further reduce the effectiveness of the vaccine.

B.1.1.7 coronavirus variant is picking up a worrisome new mutation | Ars Technica

Will coronavirus really evolved to become less deadly?

On February 1, 2021, the UK Public Health Service stated that 'we investigated more than 200,000 viruses and found that only 11 B.1.1.7 had E484K.' Although it has been suggested at the experimental stage that B.1.1.7 with E484K is caused only by mutation, more research and clinical data are needed for detailed research.

B.1.1.7 is 70% more susceptible to infection than the conventional mainstream coronavirus, and is rampant alongside the mutant strain ' 501Y.V2 ' found in South Africa. NERVTAG, an advisory board on the new coronavirus established by the British government, estimates that 'B.1.1.7 with E484K increases the risk of death by 30%.' The 501Y.V2 and the mutant strain P.1 discovered around January 2021 have also acquired E484K, and it is said that the effects of existing vaccines cannot be expected for these mutant strains.

Beth Mole, a reporter for foreign media Ars Technica and a PhD in microbiology, said, 'Existing vaccines are effective enough to prevent the new coronavirus, but new variants as long as the virus can be transmitted. Is inevitable. '

in Science, Posted by log1p_kr