Research results that'new coronavirus with strong infectivity' born by mutation is pandemic in the world



Researchers have announced that the new coronavirus strains that are prevalent in the world are 'three to six times more infectious' than the strains originally discovered.

Tracking changes in SARS-CoV-2 Spike: evidence that D614GG increases infectivity of the COVID-19 virus: Cell

https://www.cell.com/cell/fulltext/S0092-8674(20)30820-5

Dominant Coronavirus Strain Appears to Be a Mutated, More Virulent Version, Study Finds
https://www.sciencealert.com/current-dominant-strain-of-covid-19-more-infectious-than-original-study

The coronavirus may have mutated to become more infectious, Dr. Anthony Fauci says
https://www.cnbc.com/2020/07/02/the-coronavirus-may-have-mutated-to-become-more-infectious-dr-anthony-fauci-says.html

This research was announced by the joint research team of Los Alamos National Laboratory and Duke University in the United States, and Sheffield University in the United Kingdom. The team analyzed the novel coronavirus genome stored at GISAID , an international scientific institution committed to sharing information about genomic sequences.

As a result of the analysis, the research team confirmed that in the variant called 'D614G' which is prevalent in the world, there is a change in the surface protrusion called 'spike protein' used for infecting human cells. did. Additional experiments conducted by the research team showed that D614G was three to six times more capable of infecting human cells in laboratory experiments than the new coronavirus strain that was first discovered.

This D614G is considered to be the most prevalent new coronavirus strain in the world. The following chart is a graph released by the research team, showing which strains are prevalent in the world. The orange part shows D614, the first new coronavirus strain discovered, and the blue part shows D614G, which was caused by the mutation. In all regions of the world, D614 is dominant at the beginning, but it can be seen that the proportion of D614G becomes dominant over time.



When the research team investigated 999 infected people with new coronavirus infection (COVID-19) at a hospital in the United Kingdom, it was confirmed that more virus particles were present in the body of D614G infected people. However, there was no difference in 'severity' between D614G and D614.

In response to the results of this research, Director of National Institute of Allergy and Infectious Diseases

Anthony Fauche , who leads COVID-19 countermeasures in the United States, said, ``The new coronavirus is mutated to facilitate the spread of pathogens it has been suggested that. However, has come out also objection to the research results, research results and the stage's 'that have been identified remark was.

For mutations of the new corona virus, the World Health Organization (WHO) in the past 'such as corona virus RNA virus is easy to mutations compared to the other viruses' that opinion had shows. On July 2, 2020, WHO lead investigator Soumya Swaminathan told reporters that 'mutations at key sites, such as spike proteins, could impact vaccine development.' Said.



in Science, Posted by log1k_iy