Making the detection of urinary tract infections faster and cheaper with a device made according to the principle of hand spinner
Research teams in Korea and India have developed a device that can diagnose urinary tract infections such as cystitis and
A fidget spinner for the point-of-care diagnosis of urinary tract infection | Nature Biomedical Engineering
https://www.nature.com/articles/s41551-020-0557-2
A fidget spinner for point-of-care diagnostics | Nature Research Bioengineering Community
https://bioengineeringcommunity.nature.com/users/400727-yoon-kyoung-cho/posts/a-fidget-spinner-for-point-of-care-diagnostics
A fidget spinner to detect urinary tract infections | Ars Technica
https://arstechnica.com/science/2020/05/a-fidget-spinner-to-detect-urinary-tract-infections/
A urinary tract infection is a disease caused by bacteria entering the bladder through the urethral meatus. When the infection remains in the bladder, “cystitis” occurs, and when bacteria enter the kidney, “pelvic nephritis” occurs.
Due to the short distance between the anus where E. coli is present and the urethral opening, and because the urethra is short, these infections are more likely in women than in men, and more than half of women are infected at least once in their lives. It is said. It is also one of the most common bacterial infections in the world, as men are more susceptible to infections as they age.
The urine culture test, which grows the bacteria contained in the collected urine sample, is suitable for diagnosing urinary tract infections, but it is time-consuming and requires medical resources for culture. .. On the other hand, there is also a method that can be done by simply immersing a piece of paper for inspection in a urine sample, which is inexpensive, but it has the problem of not being highly reliable.
Research teams in Korea and India, led by Yoon-Kyoung Cho and others, have developed a device that uses the 'hand spinner' principle, which has been talked about as a toy.
The Hand Spinner is a toy made up of ball bearings and externally mounted blades, which was a big hit in 2017 . The following is the Guinness World Records certified 'longest spinning record of a hand spinner with one hand' movie.
Longest duration spinning a fidget spinner on one hand-Guinness World Records-YouTube
The device 'Dx-FS' made by Cho et al. Is a diagnostic hand spinner that can filter 1 ml of sample in 5 minutes by putting the sample in the part corresponding to the blade of the hand spinner. Even if you are not familiar with how to use the device, anyone can concentrate the pathogen 100 times by rotating it once or twice, and detect and identify the pathogen with the naked eye without a troublesome culture process. You will be able to.
First, a sample of 'Fluid-Assisted Separation Technology (FAST)', which is the result of the centrifugal separation technology development that Cho et al. Has been working on before Dx-FS, is attached and the sample is injected.
Rotate Dx-FS to remove FAST and add detection reagent.
This will detect the bacteria.
The cost for one inspection is $ 0.24 (about 26 yen).
In India, a combination of symptom-based diagnosis and Dx-FS was performed on 39 subjects suspected of having a urinary tract infection, and 18 patients in need of antibiotics within 50 minutes I was able to identify it to. In the past, all 39 were prescribed symptomatic antibiotics, but 21 did not have to prescribe unnecessary medication.
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