'Gene associated with high suicide risk' turned out to be present

by tazzanderson

It is said that 1.4% of deaths worldwide are deaths due to suicide, and suicide is a global problem worldwide. Such suicide has been pointed out that it is related to mental illness, especially depression, and it has also been shown that those who died of relatives suicide have a high rate of considering suicide. A British research team who conducted research on such suicide discovered that there is " gene associated with high suicide risk ".

Identification of novel genome-wide associations for suicidality in UK Biobank, genetic correlation with psychiatric disorders and polygenic association with completed suicide - ScienceDirect
https://www.sciencedirect.com/science/article/pii/S2352396419300775

What our new study reveals about the genetics and biology of suicidal behavior
https://theconversation.com/what-our-new-study-reveals-about-the-genetics-and-biology-of-suicidal-behaviour-111878

The suicidal behavior from thinking about self-injurious behavior to executing actual suicide is complicated, and it is said that there are many things not understood often. Self-injurious behavior is not necessarily carried out only by those who have problems in mind, and even people who have not experienced mental illnesses in the past may possibly perform self-injurious behavior.

Differences in genes possessed by humans have various effects, such as individual character, risk of mental illness, and dependence on alcohol and drugs. Mental illness is thought to be related to the risk of suicide, while suicide involves a lot of factors such as relationship with society, economic situation, life cycles and the environment, mental illness is a factor only I will not.

Even without a mental illness, experience such as death, divorce, economic anxiety with a loved one can fully consider despair of a person. Pessimistic people and perfectionists said that these negative life experiences may have even more serious adverse effects, leading to suicidal ideation and actual suicide. Also, if a person with an impulsive and aggressive person is under the influence of drugs or alcohol, you might hurt yourself by way of directing your gun towards you or jumping from a high place without thinking about the result of the action It seems that it may be.

by picjumbo.com

The research team at the University of Glasgow decided to use British bio banks to investigate the relationship between suicidal ideation and suicidal behaviors and genetics. UK biobank has collected a wide range of information of 500,000 people and uses information such as health condition such as height, weight, blood pressure, eating habits, exercise habits, family and individual medical history, current illness etc In addition to being possible, there are many people who submit blood samples for the purpose of analyzing DNA for analysis.

The research team conducted a questionnaire survey on 157,000 people selected from the Biobank during the six years of survey. The subject was not selected according to the presence or absence of mental illness, some people had psychiatric disorders, others said that they were not. In the questionnaire, contents such as "Have you thought that life is not worth living?" "Have you considered self-injurious behavior?" "Have you done self-injury" "Have you tried suicide?" It is said that he checked the participants' mental health.

Based on the participants' blood samples, we analyzed the differences between each DNA, self-hurting behavior and suicide thoughts and actual actions, and found that the difference in the three areas in DNA is related to thinking and behavior about suicide The research team says that it has identified what it is doing. There were also a small number of people who actually died of suicide by registrants of Bio Bank and analyzed the DNA of the suicide person, it was confirmed that many genes considered to be related to suicide were contained. Looking at the entire DNA, genes that are still associated with suicide have duplications with genes that increase the risk of several psychiatric disorders, especially when genes related to depression and anxiety disorder and genes related to high suicide risk are overlapped It is said that it was seen.

by HASTYWORDS

Research on genes associated with high suicide risk further states that "Do genes related to suicide risk affect personality?" "Does genes associated with high suicide risk alone increase suicide risk or lifestyle Or suicide risk by combining with negative events? "" Is it necessary for the gene to be useful for predicting personal suicidal behaviors? " Suicide has become a global problem, and if a useful system that can predict individual suicide is developed, it may be possible to stop suicide by care to the subject in advance.