It turns out that the health food 'turmeric' has no medicinal effect
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Turmeric, also known as turmeric, which has a distinctive yellow appearance, is said to be effective against hangovers in Japan, and is said to be effective against wounds, insect bites, and even cancer in its native India. Turmeric, also known as an ingredient in curry, is recognized as a versatile player used in folk medicine, but in fact, it has no recognized medical efficacy.
A large scientific review study shows that curcumin in turmeric has no medicinal properties — Quartz
https://qz.com/883829/a-large-scientific-review-study-shows-that-curcumin-in-turmeric-has-no-medicinal-properties/
There are various types of turmeric, and turmeric, which is widely known as an ingredient in curry in Japan, is called `` autumn turmeric '' and is characterized by its low bitterness. On the other hand, `` spring turmeric '', which has a bitter taste and strong yellow color, is used as a health food, and the curcumin contained in it has been thought to be effective.
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However, a paper by a research team at the University of Minnesota states that the substance contained in curcumin is ``unstable, chemically reactive, and a compound that cannot be absorbed by the body, so the potential for it to be useful in drug development is extremely small.'' ” has been drawn to the conclusion. When a drug is tested, it is often tested for its ability to act on a specific protein. It has now become clear that the chemical composition of curcumin has the effect of producing ``false hits'' that appear to have an effect, even though it does not actually act on proteins. I am.
These properties make people expect curcumin to be effective, and research is based on false expectations, leading to unnecessary budget expenditure. Regarding this result, Dr. Michael Walters of the University of Minnesota commented, ``The curcumin incident is a lesson for us.'' Substances with such characteristics are also called PANIS (pan-assay interference: compounds that interfere with a wide range of test methods), and are said to be cautioned as substances that cause scientific misunderstandings.
Ganda Georg, co-editor-in-chief of the medical journal ``Journal of Medicinal Chemistry,'' talks about the misunderstanding and confusion surrounding curcumin, saying, ``A lot of effort and money has been wasted on research on curcumin.'' . However, the results are still not well known, and even now, papers on the efficacy of curcumin are being submitted one after another.
The latest research has shown that the efficacy of curcumin can be said to be equivalent to a ``placebo effect'', but on the other hand, ``the research on curcumin is still insufficient'', and further investigation is needed. Research is also being conducted to understand the PANIS. However, Dr. Walter said, ``The resources devoted to researching curcumin should be used to study thousands of other chemicals that should be studied.''
The paper by the University of Minnesota research team can be viewed from the link below.
The Essential Medicinal Chemistry of Curcumin - Journal of Medicinal Chemistry (ACS Publications)
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