Whether first gene therapy for human aging is successful

ByMawoo86

Research on gene therapyBioViva USAAnnounced that it was the world's first successful gene therapy for human aging. Experimental treatment was done to the CEO of the company, and if the results of this experiment are correct, there is a possibility that the treatment of diseases related to age can greatly evolve.

First gene therapy successful against human aging - BioViva USA Inc
http://bioviva-science.com/2016/04/21/first-gene-therapy-successful-against-human-aging/

In September 2015 Elizabeth Parish, CEO of BioViva USA, received two experimental gene therapies developed in-house. One is to prevent muscle mass reduction due to aging and the other is to prevent stem cells from being exhausted due to various age-related diseases.

Originally these studies were done for the purpose of demonstrating the safety of gene therapy in modern times, but if the data in the early stages of the experiment is correct, gene therapyTelomereIt is said to be the world's first case that made it possible to expand. Up to now, telomere extension experiments have been conducted on mice, but experiments targeted at humans have not been conducted.


Telomere is the end portion of the chromosome, the part for protecting genetic information. It is said that telomere will become shorter as cell division is repeated, resulting in aging phenomenon. Conversely, if we can extend this telomere it is possible to delay aging, and an enzyme called telomerase plays its part but in human somatic cells telomerase is not expressed or even if it is expressed I have only weak activity.

In September 2015, Mr. Parrish who gathered and analyzed data from white blood cells before the experiment, Mr. Parish was shorter in telomere length than those of the same age, and earlier in life age related diseases It was said that it was subject to easy results. However, after the experiment, the same test was conducted in March 2016, and Mr. Parish's telomeres have been about 20 years longer, which is said to have shown that the leukocytes are biologically rejuvenated . Survey results are based on Brussels-based NPOsHeales MedicalAlso confirmed.

ByCaroline Davis 2010

Mr. Parrish said, "Today's treatment did not bring significant benefits to those suffering from age-related diseases, and changing lifestyles can not have a major impact on these diseases. Evolution is the best way to solve the problem, and if the result of this time is correct, we will have made history. "

BioViva will monitor Parrish's blood over the next few years. In addition, there is a possibility that it may be effective against other cells and organs if it becomes possible to rejuvenate white blood cells, there are no subjects other than Mr. Parish at present, but to aging We intend to continue research on new treatments to repair damages involved and methods combining multiple treatments.