What is "golden blood" that it has less than 0.01% of the population?

The blood type is classified into four types widely known in Japan, "A" "B" "O" "AB"ABO blood typeYaRh factorThere are various classification methods such as Rh type blood type which classifies by Among them, there are hundreds of types of blood types that are valuable globally, globally, a phantom blood type that exists only in a proportion of less than 1 in 10,000 people, commonly known as "Golden blood"Is present.

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Red blood cells are responsible for carrying oxygen to the cellular system of the whole body. If you lose a lot of blood due to accident or surgical operation, the oxygen carrying capacity in your body will be reduced, so there is a necessity to transfuse. If all human beings are of the same blood type, transfusion is very easy, but in fact there are so many types of blood types.

A maximum of 342 kinds of antigens exist on the surface of human erythrocytes, and in response to this antigen, a special protein called "antibody" is generated in the body. Also, what kind of antigens are present on the red blood cell surface is an important factor for discriminating human blood type.

Of the 342 types of antigens, about 160 blood group antigens have a high penetration rate and exist in most human blood. If it lacks any of these antigens, it means that it is a blood type different from 99% of the Earth's population, and furthermore, if there are no antigens on the red blood cell surface, it is less than 0.01% of the population It is said that it is a phantom blood type that it has only.

My blood type is "PositiveBlood transfusion, your own antibody reacts to the blood of your opponent, the immune system causes a rejection reaction, in the worst case death. That's why "blood without any antigen", that is, blood that is negative for every blood, is very rare and medically very important blood.

Forty years ago, Thomas, a 10 - year - old child then brought to the University Hospital in Geneva. Thomas is suffering from an infection, and examining his blood seems that there was no antigen for discriminating blood type. In fact, there are 342 blood group antigens, but in most cases the majority of blood group antigens have been grouped in one group, and in the Rh blood type this antigen is classified into 61 types.

However, in Thomas' s blood there were not all Rh antigens. Dr. Mari José of the University of Geneva Hospital of the time was incapable of believing this at all and she asked the laboratory in Amsterdam and Paris to analyze Thomas 'blood, so that Thomas' blood type is all antigens It turns out that it was "Rh null" which it does not have. In 2010, 43 people around the world who have the same "Rh null" as Thomas you are confirmed.

Blood types are inherited in family lines, but "Rh null" is said to be a blood type that is inherited to the next generation. So the researchers seemed to have investigated the blood type of Thomas 's relative, but as a result it turned out that Thomas' 'Rh null' type appeared by a perfect mutation, It was that it was born with a probability not to get it.

"Rh null" blood that can be transfused to patients of all blood types is referred to as Thierry Peilard director of the National Institute of Immunology and Hematology in Paris "is the golden blood." There are more than 40 people currently confirmed around the world "Rh null", among them those who will respond to transfusion are living in Brazil, Japan, China, the US and Ireland including Thomas 6 It seems to be only people.

It is said that such precious "golden blood" is stored in such a world in the UKInternational Blood Group Reference Laboratory(IBGRL) laboratory. Photographer Greg White, who took pictures of the laboratory, said, "It was the first time I saw that so much blood moved around and it was a little weird," he says.

When entering IBGRL, we first wear blue surgical gowns, special shoes and hair nets in a gray room, blood collected from England through dust-free rooms and aseptic rooms is stored I will enter the room. Also, in IBGRL, "golden blood" which has less than 0.01% of the population seems to be handled and stored completely separately so as not to mix with other blood types.

UK hospitals are expected to pay 200 dollars (about 24,000 yen) per pack regardless of the blood type when receiving blood transfusion packs from IBGRL, so when transferring a blood transfusion pack outside of the UK Will be negotiated with the destination hospital and IBGRL and the price will be decided.

in Science, Posted by logu_ii