Succeeded in fabrication of micro nano motor which can freely move within cell by combining ultrasonic wave and magnetic force

The American research team succeeded in producing autonomously propelled minimal motor that can freely move within the cell. The success of this experiment freely moves the inside of the human body and aims and targets cancer cells etc.Drug delivery systemIt seems to be closer to realization of.

Acoustic Propulsion of Nanorod Motors Inside Living Cells - Wang - 2014 - Angewandte Chemie International Edition - Wiley Online Library
http://onlinelibrary.wiley.com/doi/10.1002/anie.201309629/abstract

Nanomotors Are Controlled, for the First Time, Inside Living Cells - Eberly College of Science
http://science.psu.edu/news-and-events/2014-news/Mallouk2-2014

BBC News - Tiny motors controlled inside human cell
http://www.bbc.co.uk/news/science-environment-26136979

Dr. Tom Marok and his research team at Pennsylvania State University in the United States succeeded in developing a nano motor (ultrasonic nano motor) that can freely move inside the cell by using ultrasonic waves and magnetic force.

Aside from anything, the movie collections that the ultrasonic nano motor can understand with a single shot are as follows.

A demonstration of very active gold nanorods internalized inside HeLa cells in an acoustic field. - YouTube


A golden object moving around round cells is an ultrasonic nano motor. Various movements can be seen such as things that rotate like a drill inside the cell, things moving around the inner wall of the cell, waiting on the spot, and so on.


The interaction between gold nanorods and HeLa cells - YouTube


Ultrasonic nanomotor surrounding the outside of the cell this time.


The assembly of a rotating HeLa cell / gold rod aggregate at an acoustic nodal line in xy plane. - YouTube


Cells transported so as to be guided by ultrasonic nanomotor clinging to the surroundings.


Other cells stuck together were waiting at the destination.


Coalescence.


When zooming out it looks like this.


Cells that have become daisy are proceeding with a propulsive force while spinning like a drill.


This is a series of innumerable ultrasonic nano motors in a straight line.


The tip of the ultrasonic nano motor reaches the cell.


Ultrasonic nanomotor rotating at the center of the screen ... ...


It attracted to the magnetic force and united at the tip of the cell.


The cells in the dumpling state continue to move so as to be sandwiched between ultrasonic nano motors.


Ultrasonic nanomotor has a total length of 3 micrometers and a diameter of 300 nanometers (0.3 micrometers) and is an extremely small size smaller than human hair, gold-rutheniumIs used as a material, and it is possible to have propulsion power by changing ultrasonic vibration and magnetic field, and to join each other.


Dr. Marok says, "The autonomous motor skills of Nano motors are likely to be applied medically, one of our dreams is the style of freely" sailing "the body that has been considered fantasy so far It is a cure. "

The nanomotor which can move around freely within the cell has a major obstacle to use in the body because the chemical substance (chemical fuel) is used as driving force and the chemical fuel is toxic. Since the ultrasonic nano motor developed this time can be driven without requiring chemical fuel and has the property that it can be joined to each other,Aiming cancer cells and administering anticancer drugsDrug delivery like that,Penetrated into cancer cells and physically destroyed from the insideIt is expected to be applied to technologies to do.


In this experimentHeLa detailsAlthough it seems that the experiment in the living body is still ahead, the SF movie published in 1966 "Micro de journalismIn order to realize, mankind is one step closer, I can say that it approached.