Under development of safer and more effective analgesic than morphine

morphineIs an analgesic used for relieving pain due to severe pain and cancer but it is also classified as a narcotic because it has side effects such as nausea and constipation and dependency, is. Medicines that are more effective than morphine and have no side effects have been studied, and seems to work well with experiments using mice.

If this medicine is completed in the future, it may be useful as a cancer treatment a little.

Details are from the following.
New pain relief that is eight times stronger than morphine - Telegraph

Prostatic acid phosphatase (PAP)One kind of protein called as an analgesic may be substituted, the effect is 8 times that of morphine and the duration is more than 14 times.

It seems that PAP has confirmed that PAP changed substances causing distress from substances causing pain to substances that suppress pain, at the University of North Carolina at Chapel Hill Medical School. I injected PAP into a rat struggling with morphine, it was said that morphine had an analgesic effect of about 5 hours, PAP seems to have been effective for more than 3 days. Mark Zylka, an assistant professor of molecular physiology, seemed to have been more effective than morphine which is commonly used. It seems that such effects can not be obtained simply by hitting the camphor agent.

When I feel painAdenosine triphosphate (ATP)It seems that PAP will generate ATP as a substance to suppress pain. In addition, even if PAP is used, side effects are less likely to occur than morphine, so it seems that at the moment there has been almost no confirmation of side effects and brain-affecting actions so far.

It has not yet been put into practical use and it seems that it will take time to make tablets. Zylka says there is plenty of potential in the future for PAP to become commonly used as an analgesic.