It is clear that the long-term case of the new coronavirus `` Omicron strain '' is lower than other mutant strains



The Omicron strain (B.1.1.529 lineage), one of the novel coronavirus (SARS-CoV-2) variants, has spread rapidly around the world since it was first detected in November 2021. It is raging over the mutant strains of. Research papers on such Omicron strains have revealed that Omicron strains have a lower probability of becoming long-term cases than other mutant strains.

Risk of long COVID associated with delta versus omicron variants of SARS-CoV-2 - The Lancet

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00941-2/fulltext

According to data from Our World in Data, which compiles statistics on the COVID-19 pandemic in every country in the world, Omicron was among the most reported COVID-19 cases in Europe between December 2021 and March 2022. The strain has surpassed the number of cases for other variants.

According to a paper titled 'Long-term Risk for Delta and Omicron Strains of Novel Coronavirus,' published in June 2022 in the journal The Lancet , Omicron strains have been reported to date, at least in vaccinated populations. Although it was found to cause less severe acute disease than the previous variant, it has also been noted that many people may be experiencing long-term symptoms.



This study compares long-term cases of the Omicron and Delta strains of novel coronavirus disease (COVID-19). The definition of a long-term case is ``new symptoms or ongoing symptoms have occurred more than 4 weeks after the onset of COVID-19,'' which is the

National Institutes of Health (NIH ) guidelines. The study analyzed data collected by a COVID-19 symptom tracking app developed by a research team at King's College London.

The subjects surveyed had no experience of being infected with COVID-19 before vaccination, and had SARS-CoV after vaccination during the period from December 20, 2021 to March 9, 2022 (about two and a half months). -2 British infected adults who tested positive for 2 PCR tests or lateral flow antigen tests and continued to report cases on the app at least once a week for at least 28 days (4 weeks) after testing positive (5 6,003 people). It is estimated that more than 70% of these cases were infected with the Omicron strain, so the cases during the same period are basically regarded as 'Omicron strain cases'.

The research team referred to this 'Omicron strain case' as case data for 41,361 adult British individuals who tested positive for the same test between June 1, 2021 and November 27, 2021. Compare. It is estimated that more than 70% of the cases during the same period were infected with the delta strain, so the cases during the same period are referred to as 'delta strain cases' in the study.



A comparison of the two data shows that women have a higher incidence than men, with 55% of the 'Omicron strain cases' and 59% of the 'Delta strain cases' being women. The 'Omicron strain cases' and 'Delta strain cases' were of similar age, with an average age of 53 years and a prevalence of comorbidities of 19%. Also, the

IMD score is slightly lower for the Omicron strain than for the Delta strain.

Furthermore, in order to evaluate the relationship between long-term cases of COVID-19 and the duration of infection, we investigated the gender, IMD, age, presence of comorbidities, and vaccination status (number of times Inoculation or not), body mass index (BMI), etc. are compared. In addition, the infected people were divided into three groups according to the time from vaccination to infection with COVID-19 (3 months, 3-6 months, 6 months or more), and immunity increased as time passed after vaccination. We are analyzing it after considering how much it will drop.

As a result of the analysis, 2501 out of 56,003 'Omicron strain cases' (about 4.5%) experienced long-term cases, while 4469 out of 41,361 'Delta strain cases' (10.8%) experienced long-term cases. Also, even when divided into groups by time from vaccination to infection with COVID-19 (3 months, 3-6 months, 6 months or more), 'Omicron strain cases' are higher than 'Delta strain cases'. The probability of becoming a long-term case is low.



This study is the first peer-reviewed paper to report the risks associated with long-term cases of the Omicron strain. The reason why this study did not include data on long-term COVID-19 cases in unvaccinated people was ``the data were insufficient and it was difficult to consider the effects in children''.

in Science, Posted by logu_ii