Research results show that 'omega 3 fatty acids' contained in blue fish are effective for migraine
Dietary alteration of n-3 and n-6 fatty acids for headache reduction in adults with migraine: randomized controlled trial | The BMJ
https://www.bmj.com/content/374/bmj.n1448
Mediterranean diet with oily fish could help reduce migraine frequency | Food | The Guardian
https://www.theguardian.com/food/2021/jun/30/mediterranean-diet-with-oily-fish-could-help-reduce-migraine-frequency
Dr. Christopher Ramsden and colleagues from the National Institute on Aging have announced new findings that omega 3 fatty acids are effective in migraine headaches. Dr. Ramsden and colleagues investigated the effects of omega-3 and omega-6 fatty acid intake on the frequency and severity of migraine headaches in 182 people who develop migraine headaches 5 to 20 days a month.
Omega-3 fatty acids, which are mainly contained in fatty fish such as tuna, bristle and mackerel, and nuts such as walnuts, and omega-6 fatty acids, which are contained in refined oils such as soybean oil and corn oil, both have the effect of adjusting pain called oxylipin. Oxylipin derived from omega-3 fatty acid suppresses pain, and oxylipin derived from omega-6 fatty acid amplifies pain, which are contradictory effects.
In this experiment, there are three types: 'general amount of both omega-3 fatty acid and omega-6 fatty acid', 'increased amount of omega-3 fatty acid & normal amount of omega-6 fatty acid', and 'increased amount of omega-3 fatty acid & decreased amount of omega-6 fatty acid'. Subjects were randomly assigned one of the diets, and each subject continued the assigned diet for 16 weeks. In addition, each diet was set so that the contents would be similar to each other, and the increase or decrease of omega-3 fatty acids and omega-6 fatty acids was adjusted according to the types of cooking oil and butter and ingredients such as fish mainly composed of protein.
Examining the subjects 16 weeks later, the intervention diet of 'increased omega-3 fatty acids & normal amount of omega-6 fatty acids' and 'increased omega-3 fatty acids & decreased omega-6 fatty acids' increased the production of oxylipin to relieve pain. The severity of migraine did not change significantly, while the frequency of migraine tended to decrease significantly. In the 'Omega 3 fatty acid increased & omega 6 fatty acid normal amount' group, the daily headache time decreased by 1.3 hours & the number of days of headache decreased by 2 days per month, 'Omega 3 fatty acid increased & omega 6 fatty acid increased' In the 'weight loss' group, the daily headache time was reduced by 1.7 hours and the number of headache occurrence days was reduced by 4 days per month.
In addition, since most of the subjects this time were women, Dr. Ramsden et al. Possibility that 'different results may be obtained in the case of children, men, and the elderly' and 'Omega 3 taken from other than fish' Fatty acids may give different results. '
It's also unclear whether the results are purely from omega-3 fatty acids. Tom Sanders, Professor Emeritus of Nutrition and Diet at Kings College London, said, 'For example, if you increase your salmon intake, you will not only get long-chain omega 3 fatty acids, but some other things such as vitamin D and selenium. It will also increase your intake of micronutrients, 'he said, pointing out that some nutrients in foods rich in omega 3 fatty acids may have helped.
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