First research result to diagnose dinosaur as cancer is reported


by

Fred Wierum

Previous studies have found that Tyrannosaurus suffered from gout, but a recent study examining dinosaur fossils by orthopedic specialists showed that dinosaurs had osteosarcoma , a cancer of the bones they had before birth. It was discovered. This is the first time a dinosaur has been diagnosed with cancer.

First case of osteosarcoma in a dinosaur: a multimodal diagnosis-The Lancet Oncology
https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(20)30171-6/fulltext

Malignant cancer diagnosed in a dinosaur for the first time – Brighter World
https://brighterworld.mcmaster.ca/articles/malignant-cancer-diagnosed-in-a-dinosaur-for-the-first-time/

New Research Shows Dinosaurs Suffered From Malignant Cancer, Too :NPR
https://www.npr.org/2020/08/04/899060875/scientists-discover-malignant-cancer-in-a-dinosaur

Seper Ekhtiari, who studies orthopedics at McMaster University in Canada, and a research team at the Royal Ontario Museum published a paper published in the medical journal The Lancet Oncology on August 1, 2020 in a dinosaur fossil. Reported that traces of osteosarcoma were found.

Below are the fossils in question. The fossil, which was housed in the Royal Ontario Museum, is said to be a kind of hind leg bone of Centrosaurus that lived in the area centered around Canada 76 to 77 million years ago. It has been thought that this bone is in the process of healing a fracture because the left side has a strange and bulging shape.



However, doctors at McMaster University who visited the Royal Ontario Museum in 2017 were so curious that the fossils in question were so strange that they decided to investigate further. During the study, the research team conducted a

CT scan of the fossil to examine the internal structure.

The result is the image below. The normal part is colored gray, the medullary cavity containing the bone marrow is red, and the part that seems to be an abnormal tumor is colored yellow. With a high-precision CT scan, the research team found that large areas of the bone were tumors.



The team will further investigate fossil tumors by taking thin sections of fossils for microscopic observation and comparing them to normal fossils of the same species and human bones diagnosed with osteosarcoma. did.

Of the images below, the left is the fossil of this time and the right is the normal fossil that is supposed to belong to the same dinosaur. If you compare the two bones, you can see at a glance that they are completely different in length and shape. Also, when observing the thin slices of bone with a microscope, large lesions were observed at the cellular level.



Based on the results of these investigations, the research team determined that the tumor found in the fossil in question was 'bone sarcoma,' a malignant bone tumor. ``The approach we took in this case is very similar to examining a human patient with an unknown new tumor,'' said Ekhtiari, a researcher who analyzed the tumor in detail. ..

The fossils surveyed this time were bones of an adult Centrosaurus, which were excavated with numerous fossils of the same species. Therefore, it is believed that the cause of death of fossil owners was not predation or morbidity, but that they were flooded with other herds.



David Evans of the Royal Ontario Museum, a co-author of the paper and an expert on horned dragons , said: ``The cancer is highly invasive and is thought to have caused significant damage to the patient. It would have been terrible if the owners of the cattle were attacked by predators such as Tyrannosaurus before they were born. It may be because it was protected inside.'

“Even though dinosaurs are often thought to be mythical and mighty creatures, our findings show that they too suffered from our immediate illnesses and cancer. This bizarre discovery, which highlights that fact, brings them back to life even more.'

in Science,   Creature, Posted by log1l_ks