'The effect on the heart' of the new coronavirus was against the expectation of doctors

A new coronavirus infection (COVID-19) has been shown to damage patients to major organs other than the lungs, but a new pathological autopsy revealed that the heart would be damaged. It turned out that it was different from the 'inflammation of the myocardium' that was used.

Unexpected Features of Cardiac Pathology in COVID-19 Infection | Circulation


Autopsies reveal surprising cardiac changes in COVID-19 patients --Science Daily

COVID-19 but has been mainly reported pneumonia symptoms, impact on the major organs such as heart, lung, kidney is not yet clear, in the organs to generate a blood clot from that the 'blood of the problem' is also pointed out Has been done .

A research team led by Richard Van der Heide, a pathologist at the Louisiana State University Center for Health Sciences New Orleans, died to investigate the effect of the new coronavirus (SARS-CoV-2) on the heart of COVID-19 patients. Performed autopsy of the patient. As a result, unlike SARS which was prevalent in 2002, it was revealed that SARS-CoV-2 does not exist in myocardial cells and that there is no occlusion due to thrombus in the coronary arteries.

'We found significant macroscopic and microscopic changes that challenge the idea that'SARS-CoV-2 infection causes typical myocarditis',' Heide said in a survey. 'While the mechanism by which COVID-19 damages the heart is unknown, we have some thoughts about the direction of the study to understand the disease and provide potential treatments.'

Previous studies have shown that COVID-19 patients suffer from

diffuse alveolar damage (DAD), which damages the lungs, and thrombosis and bleeding in small blood vessels and capillaries in the lungs of severely ill patients. It has been shown to be the cause of death.

'In light of the expanding right ventricle and these findings, we suspect that extreme stress on the heart could cause acute lung disease,' said Dr. Sharon Fox of the Louisiana State University School of Medicine. States.

Researchers have also discovered that some of the endothelial cells in the heart have a viral infection. Although the infection is at a very low level, it is fully possible that a cytokine storm will occur and cause cell death, resulting in heart failure. 'If inflammatory cells could cross the heart without being present in the native connective tissue, the role of cytokine-induced endothelial damage cannot be ruled out,' Heide said.

The autopsy was performed on 22 COVID-19 patients who died at the Louisiana State University Center for Health Sciences New Orleans, most of them African-American. Of these, 10 were male and 12 were female, ages 44-79. Patients were basically healthy, but most were hypertensive and half had type 2 diabetes and obesity.

in Science, Posted by darkhorse_log